Lipostone 20 mg (Rosuvastatin Calcium)

Adult dosage

This medication is administered at an initial dose of 5 mg once daily, which may be increased to a maintenance dose of 10 mg to a maximum of 20 mg once daily if needed. Administration can occur at any time during the day, regardless of meals; dosage adjustments should be made based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or longer.

Children's dosage

In pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, a daily dosage of 5 mg to 20 mg may be administered once daily, with dosage adjusted according to individual treatment goals at intervals of 4 weeks or longer.

This medication should not be used in certain patients. For example, patients who are allergic to this medication, those with severe liver dysfunction, those with myopathies, and pregnant or breastfeeding women should not take this medication. Furthermore, the use of this drug may be restricted in patients with severely impaired kidney function or those taking certain medications concurrently. Patients at higher risk of muscle-related side effects should avoid high doses of this medication. It is important to regularly monitor liver function and muscle condition while taking this medication. Individuals with a history of liver disease or those who consume alcohol excessively should exercise increased caution, as should those with hypothyroidism or other muscle disorders. If symptoms such as myalgia, muscle weakness, or muscle cramps occur, the physician should be notified immediately, and the medication may need to be discontinued if necessary. Additionally, it is advisable to avoid performing muscle enzyme tests after intense exercise while on this medication. This medication can raise blood sugar levels in some patients, so individuals at risk of diabetes must strictly manage their blood glucose levels. Rarely, serious allergic reactions or liver dysfunction may occur; therefore, if symptoms such as skin rashes, jaundice, or severe fatigue develop, treatment should be stopped immediately and consultation with healthcare professionals should occur. This medication may interact with other drugs, so it is essential to inform the doctor or pharmacist of any currently taken medications. Caution is especially needed when used with certain antiviral, immunosuppressive, antibiotic, or fibrate drugs. Women of childbearing potential should ensure proper contraceptive measures before taking this medication, and it should be avoided during pregnancy. Its use is also not recommended while breastfeeding. In case of overdose, there is no specific antidote, so one must go to the hospital immediately for treatment according to symptoms and monitor liver function and muscle enzyme levels. Finally, while this medication is not known to significantly affect driving or machinery operation, it can rarely cause dizziness, so caution is advised.

Serious side effects

Hypersensitivity reactions including rash and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), chest tightness, difficulty breathing, respiratory distress, respiratory anomalies accompanied by cough and fever, yellowing of the skin or eyes (jaundice), generalized malaise, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output, severe systemic symptoms

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and hives
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly sealed container to protect it from air and moisture and should ideally be kept at room temperature between 1°C and 30°C. Storing it this way helps maintain the medication's effectiveness over time.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle