Boncure Injection (Ibandronate Sodium Trihydrate)

Adult administration

Administer 3mg intravenously once every 3 months over 15 - 30 seconds.

This medication must be administered intravenously, as administration into arteries or around veins may cause tissue damage. Patients with a known allergy to this medication or its components, as well as those with untreated hypocalcemia, should not use this drug. Potential side effects during use may include gastrointestinal issues, muscle pain, joint pain, fatigue, headaches, and rashes, which are mostly mild to moderate. Some patients have reported transient influenza-like symptoms, vasculitis, hypersensitivity reactions, and severe skin reactions. Osteonecrosis of the jaw can occur rarely, so cancer patients or those with poor oral hygiene should receive dental care beforehand and avoid excessive dental treatment while under therapy. Patients receiving this medication should ensure adequate intake of calcium and vitamin D, and regular check-ups are necessary if they have renal function issues or other diseases. If pain in the thigh or groin occurs, the possibility of atypical fractures should be suspected, and consultation with a physician is recommended. It is safer for pregnant or breastfeeding women not to use this medication, and the safety for children under 18 years old has not been established. Caution is needed as overdose may affect kidney and liver functions, and if overdose is suspected, immediate consultation with healthcare professionals is required. This medication should not be mixed with calcium-containing solutions or other intravenous drugs and must only be administered by intravenous injection. After use, the syringe and needle should not be reused and should be disposed of safely.

Serious side effects

• Urticaria
• severe swelling (edema)
• anaphylactic reactions
• shock
• severe allergic reactions
• Stevens-Johnson syndrome
• erythema multiforme
• bullous dermatitis
• severe skin adverse reactions
• angioedema

Mild side effects

• Gastritis
• diarrhea
• abdominal pain
• dyspepsia
• nausea
• constipation
• musculoskeletal pain
• joint pain
• muscle pain
• influenza-like illness

This medication should be stored in a tightly sealed container to prevent air from entering and at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the drug's effectiveness.

Appearance

It is an injectable solution in a colorless and transparent prefilled syringe, with a single-use needle attached.

Package unit

1 vial/3mL/prefilled syringe