Lozasca Tablet 5/50 Milligrams

Adult dose

The recommended dose of this medication is 1 tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time daily (e.g., in the morning). Typically, this drug 5/50 milligrams is administered once daily, and if blood pressure remains inadequately controlled after 2 weeks, the dose may be increased to 1 tablet of 10/50 milligrams once daily.

Child dose

The safety and efficacy of this drug have not been established in pediatric patients under 18 years of age, so its use is not recommended.

This drug may cause serious harm to the fetus, especially in the second and third trimesters of pregnancy, and should be discontinued immediately if pregnancy is confirmed. Taking this medication during pregnancy can lead to severe issues such as impaired fetal kidney function, decreased amniotic fluid, and craniofacial deformities. Women who may become pregnant should avoid this medication and it must not be used during pregnancy. Patients with reduced effective blood volume, such as those taking diuretics, should stabilize their condition before taking this medication and it is advisable not to administer this drug. Patients with hypersensitivity to any of the ingredients, severe liver dysfunction, severe aortic stenosis, or in a state of shock should not take this medication. Due to the blood pressure-lowering effects, dizziness or drowsiness may occur, and caution should be exercised when engaging in potentially dangerous activities such as working at heights or driving. This medication should be used with caution in patients with impaired kidney function or hyperkalemia, and potassium levels and kidney function should be regularly monitored through blood tests. Caution is also needed when used in conjunction with other antihypertensive agents due to the potential for enhanced blood pressure-lowering effects. Taking this medication with grapefruit juice may excessively increase its effects, so co-administration should be avoided. Nursing women are advised not to take this medication, and it is not recommended for children or adolescents under 18 years of age as safety and efficacy have not been established. In case of overdose, severe hypotension and increased heart rate may occur, necessitating immediate contact with a medical institution to receive appropriate treatment. Medications should be stored out of reach of children, and it is advisable not to transfer them to other containers.

Serious side effects

Hives, severe swelling (edema), chest discomfort, difficulty breathing, paleness, angioedema (swelling of lips and eyelids with facial rash), angioedema (laryngeal/glottic swelling that may cause airway obstruction, swelling of face/lips/pharynx/tongue), severe allergic reactions, severe skin reactions, skin peeling, pain in oral/ocular mucosa, severe edema, urination abnormalities, markedly reduced urine output, severe widespread edema and blood pressure

Mild side effects

• Dizziness
• headache
• drowsiness
• weakness
• chest discomfort
• chest pain
• early satiety
• peripheral edema
• pitting edema
• abdominal discomfort

This medication may be sensitive to air and moisture, thus it should be stored in a tightly sealed container. It is also advisable to keep it at room temperature, ideally between 1°C and 30°C. Proper storage can help maintain the effectiveness of the medication.

Appearance

White rectangular film-coated tablets

Package unit

For domestic use - 30 tablets/bottle [for domestic use], for export - 30 tablets/PTP [10 tablets/PTP x 3]