Duo-extended-release 5/500 milligrams

Adult dose

This drug is generally administered once daily with the evening meal. The maximum dosage is once daily dapagliflozin 10mg/extended-release metformin 2000mg, taken as 2 tablets of 5mg/1000mg. If there has been no prior experience with diabetes medication treatments, the recommended starting dose when used as initial therapy is 1 tablet of 5mg/500mg or 10mg/500mg, administered once daily. Regarding gastrointestinal side effects of metformin.

This drug is used for diabetes treatment and helps control blood sugar. Although very rare, this drug can cause a serious metabolic complication known as lactic acidosis. Lactic acidosis is a condition in which the level of lactic acid in the blood rises and acidity increases, which can be life-threatening if not treated. Therefore, patients with poor kidney function or those with heart or liver issues should be especially cautious. Additionally, the risk of hypoglycemia may increase when this drug is used with insulin or sulfonylureas, so hypoglycemic symptoms should be closely monitored during co-administration. Patients with severely impaired kidney function, dehydration, acute infections, severe heart failure, or acute myocardial infarction should not use this drug, and it should be temporarily discontinued before and after tests using radiographic contrast agents. Patients with decreased fluid volume or low blood pressure, the elderly, and those on diuretics should be closely monitored for the risk of hypotension or deterioration of kidney function before and after administering this drug. This drug can cause genital and urinary tract infections, and if symptoms of infection appear, medical personnel should be notified immediately. There may be a deficiency in vitamin B12, so if taken for a long time, it is advisable to regularly check vitamin B12 levels in the blood. Women who are pregnant or may become pregnant, as well as breastfeeding women, should not use this drug, and use in children and those over 80 years old should be with caution. In case of overdose, appropriate treatment is necessary, and especially in patients with reduced kidney function, there is a risk of drug accumulation in the body, so caution is advised. Alcohol consumption should be avoided while taking this drug, and care should be taken to ensure that there are no symptoms of hypoglycemia or dehydration by monitoring meals and fluid intake. Finally, this drug should be stored out of reach of children, and kept in its original container to prevent misuse or degradation of quality.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• ketoacidosis
• urosepsis
• pyelonephritis
• acute kidney injury
• kidney dysfunction
• necrotizing fasciitis
• acute cholecystitis
• Guillain-Barré syndrome

Mild side effects

• Genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• dry mouth
• dizziness
• constipation
• back pain
• dysuria
• polyuria

This drug should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps to preserve the effectiveness and safety of the drug for a long time.

Appearance

Orange, biconvex, rectangular film-coated tablet

Package unit

30 tablets (6 tablets x 5) / box