Cerezen Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. Osteoarthritis (degenerative arthritis): Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. Rheumatoid arthritis: Administer celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, another treatment should be considered. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if the patient frequently consumes alcohol in amounts greater than a certain daily limit, as it may increase the risk of gastrointestinal bleeding. This medication may increase the risk of cardiovascular problems such as heart attack or stroke, so it should be used at the minimum effective dose for the shortest duration possible. If symptoms of cardiovascular issues appear during the course of taking this medicine, such as chest pain or shortness of breath, immediate consultation with a healthcare professional is required. Patients with a history of gastric ulcers or bleeding should be particularly cautious while taking this medication and should closely monitor for symptoms of gastrointestinal bleeding. Elderly patients or those with gastrointestinal disorders are at higher risk of serious side effects such as gastrointestinal bleeding while taking this medication, and special care is required. Patients with compromised liver or kidney function, heart failure, or hypertension should consult their healthcare professional before taking this medication and require regular monitoring during treatment. This medication is not administered to patients with specific allergy histories, to pregnant or nursing women, or to those with severe liver or kidney diseases. Dizziness or drowsiness may occur during treatment, so it is advisable to avoid driving or operating machinery. This medication may interact with other drugs, so it is essential to inform the healthcare professional if taken with blood pressure medications, anticoagulants, antidepressants, etc. Women planning pregnancy should consult a healthcare professional before deciding to take this medication, as it may affect reproductive capability. Long-term use of this medication requires regular assessment of liver and kidney function and blood tests to check for side effects, and any unusual symptoms should prompt immediate cessation and consultation with a healthcare professional. If rashes, mucosal lesions, blisters, or itching occur while taking this medication, usage should be stopped immediately and healthcare professionals should be informed. Exceeding the prescribed dosage or overdose may cause serious symptoms such as vomiting, drowsiness, and gastrointestinal bleeding, necessitating immediate emergency treatment. This medication is generally not used in children or adolescents due to lack of established safety and efficacy.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distension, gastric ulcer, dental disorders, duodenal ulcer, esophageal ulcer, bowel perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, urinary frequency, kidney stones, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute kidney failure, interstitial nephritis, headache, leg cramps, tension headaches, sensory reduction, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenzal syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized blistering fixed drug rash, fixed drug rash, menstrual disorders, female infertility, chest pain, nausea, constipation, thirst, ulcerative stomatitis, gastritis, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, respiratory distress, elevated ALT, hearing loss, anaphylaxis reaction, hallucinations, cerebral hemorrhage, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, acute kidney failure, hyponatremia

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is recommended to keep it at room temperature between 15 and 30 degrees Celsius, which helps to maintain its effectiveness for longer.

Appearance

A white capsule filled with white to pale yellow powder, with yellow stripes on the top and bottom.

Package unit

100 capsules/bottle, 30 capsules/bottle