Krezid 5 mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is 5 mg once daily, and for those needing further reduction in LDL cholesterol levels, the maintenance dose may be adjusted accordingly. The maintenance dose is usually 10 mg once daily, with most patients controlled at this dose. The maintenance dose must be adjusted appropriately based on LDL cholesterol levels, treatment goals, and the patient's response at intervals of 4 weeks or longer, with a maximum increase to 20 mg per day.

This medication should not be administered to certain patients. For example, it should not be used in patients who are allergic to this medication or have severe liver dysfunction, patients with muscle diseases, patients with very poor renal function, or women who are pregnant or breastfeeding. Additionally, this medication may cause muscle-related side effects, so patients at high risk of myalgia or myopathy should use it cautiously and consult a doctor immediately if any unusual muscle symptoms occur during treatment. Patients with impaired liver function or those who consume alcohol excessively should undergo liver function tests before using this medication and should have regular liver function tests during treatment. This medication may increase blood glucose levels in some patients, so those at risk of diabetes should monitor their blood sugar regularly. Moreover, this medication may act differently in the body based on certain genetic factors, so dosage adjustment may be necessary based on the patient's condition. Severe skin reactions may occur, so if any symptoms such as skin rash or severe itching appear, the use of the drug should be stopped immediately and medical advice should be sought. This medication may interact with other drugs, so it is essential to inform the physician or pharmacist about any medications currently being taken, especially when combined with drugs that may affect the muscles. Women who are pregnant or planning to become pregnant should consult a specialist before using this medication and must use appropriate contraception. In the event of overdose, there is no specific antidote, so it is essential to visit a medical institution immediately and receive appropriate treatment while closely monitoring liver function and muscle status. This medication is known not to have a significant impact on the ability to drive or operate machinery, but caution should be taken as dizziness may occur after dosing.

Serious side effects

Urticaria, hypersensitivity reaction including angioedema, chest tightness, difficulty breathing, respiratory abnormalities accompanied by cough and fever, jaundice, hepatitis, severe muscle weakness, ophthalmoplegia, thrombocytopenia, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, rhabdomyolysis, acute renal failure, oliguria, both fatal and non-fatal liver failure, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• fatigue
• hematuria
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps retain the medication's efficacy for a longer duration.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle