Medication info
Loxko Tablet (Sodium Loxoprofen Hydrate)

Loxko Tablet (Sodium Loxoprofen Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Loxoprofen Sodium Hydrate›68.1mg / 1 tablet
Manufacturer / importer
(주)오스코리아제약
Appearance
White round tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201502705 · Approved 2015.04.30 · Insurance code 629700540

Summary

Main use
Anti-inflammatory and analgesic effects for chronic rheumatoid arthritis and osteoarthritis, as well as antipyretic and analgesic effects for acute upper respiratory infections
Who takes it
Adults
Adult dose
1. For indications and effects 1 and 2: Adults: Administer sodium loxoprofen (anhydrous) 60 mg orally three times a day. For single-dose therapy, administer 60 to 120 mg orally. 2. For indication and effect 3: Adults: Administer sodium loxoprofen (anhydrous) 60 mg orally. In principle, a maximum of 180 mg can be given per day, twice a day. It is advisable to avoid taking it on an empty stomach.

Ingredients

Manufacturer
(주)오스코리아제약

Efficacy & effects

Anti-inflammatory and analgesic effects for chronic rheumatoid arthritis and osteoarthritis, as well as antipyretic and analgesic effects for acute upper respiratory infections

  • Chronic rheumatoid arthritis
  • osteoarthritis
  • low back pain
  • periarthritis of the shoulder
  • cervical radiculopathy
  • post-operative pain
  • post-traumatic pain
  • post-extraction pain
  • acute upper respiratory infection
  • acute bronchitis
View approved original text

This medication is effective in reducing inflammation and pain associated with various joint and muscle-related conditions such as chronic rheumatoid arthritis, osteoarthritis (degenerative arthritis), low back pain, periarthritis of the shoulder, and cervical radiculopathy. It is also used to relieve inflammation and pain following surgery, trauma, or tooth extraction. It reduces fever and pain associated with upper respiratory infections, including acute upper respiratory infections and acute bronchitis. It is widely used to improve inflammation, pain, and fever related to various diseases and symptoms.

How to take

Adult dose

1. For indications and effects 1 and 2: Adults: Administer sodium loxoprofen (anhydrous) 60 mg orally three times a day. For single-dose therapy, administer 60 to 120 mg orally. 2. For indication and effect 3: Adults: Administer sodium loxoprofen (anhydrous) 60 mg orally. In principle, a maximum of 180 mg can be given per day, twice a day. It is advisable to avoid taking it on an empty stomach.

Precautions

This medication should not be used by individuals who regularly consume more than three glasses of alcohol a day, as it may increase the risk of gastric bleeding; consultation with a doctor or pharmacist is essential. This medication may increase the risk of cardiovascular disease and can lead to serious complications such as myocardial infarction or stroke. Even if there is no history of cardiovascular disease, symptoms related to the cardiovascular system should be monitored closely during use, and immediate consultation with medical professionals is required if symptoms appear. Serious gastrointestinal issues such as gastric bleeding, ulcers, or perforation may occur, especially in the elderly or those with a history of gastrointestinal disorders. This medication is contraindicated in patients with a history of peptic ulcer, severe blood disorders, serious liver or kidney diseases, severe heart failure, pregnant women in late pregnancy, nursing mothers, and individuals with certain genetic disorders. Patients with a prior allergic reaction to this medication or similar drugs should also avoid its use. Patients with a history of peptic ulcer, kidney, liver, or heart disorders, the elderly, and hypertensive patients should be monitored more carefully during treatment. If any allergic symptoms such as rash, itching, or difficulty breathing occur during use, discontinue taking the medication immediately and inform healthcare providers. If gastrointestinal symptoms such as abdominal pain, nausea, vomiting, or bloody stools occur, discontinue medication and seek medical attention. Neurological side effects such as drowsiness, dizziness, or headache may occur, requiring caution when driving or operating machinery. There may be signs of liver dysfunction or decreased kidney function, so regular testing is necessary, and if abnormalities are found, discontinuation of the medication is recommended. It is advisable not to take this medication with other nonsteroidal anti-inflammatory drugs. Additionally, drug interactions may occur with certain antihypertensives, anticoagulants, and antibiotics, so patients should inform healthcare providers about any medications they are taking. During pregnancy, especially in late stages, it may pose risks to the fetus and should not be used; women of childbearing potential should use it with caution. Nursing mothers should not take this medication for safety reasons. Safety in children has not been established, so it is preferable not to administer it to children. Elderly patients are at a higher risk for adverse effects, so caution is required during use. This medication should be stored out of reach of children, and transferring it to another container can adversely affect the quality of the medication.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, gastrointestinal bleeding, shock, symptoms resembling anaphylaxis, peptic ulcers, perforation, gastrointestinal bleeding in the small or large intestines, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, acute generalized exanthematous pustulosis, respiratory distress, asthma

Mild side effects

  • Rash
  • itching
  • fever
  • abdominal pain
  • gastrointestinal discomfort
  • loss of appetite
  • nausea
  • vomiting
  • diarrhea
  • constipation
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  • chest tightness
  • indigestion
  • oral inflammation
  • dry mouth
  • abdominal bloating
  • drowsiness
  • numbness
  • dizziness
  • headache
  • anemia
  • hemolytic anemia
  • leukopenia
  • thrombocytopenia
  • eosinophilia
  • hematuria
  • proteinuria
  • fever
  • malaise
  • chest pain
  • anxiety
  • fatigue
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1°C and 30°C at room temperature. This will help preserve the medication's effectiveness and safety.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.