Bindakel Capsule 20 mg (Tafamidis Meglumine)

Adult dose

The recommended dose of this medicine is 20mg orally once daily. This medicine is for oral use. Swallow the soft capsule whole without crushing or cutting it. This medicine may be taken with or without food. If vomiting occurs immediately after taking this medicine, check the vomit for the medicine. If the medicine is found in the vomit, take an additional dose as soon as possible. If no capsule is found, do not take an additional dose; resume taking this medicine as usual the following day. No dose adjustment is required in patients with mild to moderate hepatic impairment.

Women of childbearing potential must use adequate contraception during treatment and for 1 month after stopping the medication. This medication contains sorbitol, so patients with hereditary fructose intolerance should not take it. Patients with a known allergy to this medication or its components should not use it. During treatment, urinary infections and vaginal infections may occur, along with gastrointestinal discomfort such as diarrhea or upper abdominal pain. Patients with mild to moderate hepatic impairment may use the medication, but safety in patients with severe liver impairment is not determined. There are no clinical studies for patients with impaired renal function. The effects of this medication on driving or operating machinery have not been studied, so caution is needed. This medication may interact with some drugs; therefore, if you are taking other medications, consult your physician or pharmacist. Care should be taken, especially when used with drugs such as methotrexate and rosuvastatin. It is advisable for pregnant women or those who may become pregnant to avoid this medication, and it is also best for breastfeeding women not to take it. There is no experience with use in children, so it is not administered to pediatric patients. Elderly patients over 65 can take it, but there may be a slight decrease in the drug clearance rate. This medication may affect thyroid hormone levels in the blood but does not cause thyroid dysfunction. Reports of overdose are rare, and mild side effects may occur with high doses. It should be kept out of reach of children and stored in the original container. In nonclinical studies, this medication may affect the liver and kidneys, but these effects are generally reversible. In pregnancy animal studies, it may affect the fetus, so use is not recommended during pregnancy. It can also be excreted in breast milk, which may pose risks to infants. Consult a doctor before deciding on the use of this medication during pregnancy and breastfeeding.

• Urinary tract infection
• vaginal infection
• diarrhea
• upper abdominal pain
• mild molluscum contagiosum

Store this medication in a tightly sealed container to prevent air or moisture from entering, and keep it at a cool temperature of 25 degrees Celsius or below. This storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Yellow opaque elongated capsule containing a suspension that is white to pink

Package unit

30 capsules/box [(10 capsules/PTP x 3)/box]