Sitagliptin Tablet 50 mg (Sitagliptin Phosphate Hydrate)

Adult dose

This medication is administered once daily at a dosage of 100 mg for either monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are required: - Mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment needed - Moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): No dosage adjustment needed - Moderate renal impairment (

This medication may cause severe allergic reactions after administration; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, use should be immediately stopped and medical personnel should be notified. This medication may cause severe inflammation of the pancreas (pancreatitis); therefore, if symptoms like abdominal pain, vomiting, or nausea occur, medication should be stopped immediately and the doctor should be consulted. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and should also not be administered if there is a history of allergic reactions to this medication or its components. For patients with impaired kidney function, the dosage of this medication should be adjusted; therefore, regular kidney function tests should be conducted, and the prescription should be followed as directed by a healthcare professional. When used with other diabetes medications that have hypoglycemic risks, attention should be given to hypoglycemic symptoms, and dosage adjustments of other medications may be necessary. This medication may cause side effects such as headaches, upper respiratory infections, nasopharyngitis, diarrhea, nausea, etc., so if symptoms are severe or persistent, consultation with a healthcare professional is recommended. Severe joint pain or blistering skin conditions may occur; if these symptoms appear, notify the doctor immediately and stop using the medication. Women who are pregnant or breastfeeding should avoid using this medication, and its safety and efficacy in children under 18 have not been confirmed. In the elderly, impaired kidney function is common, so kidney function tests should be performed before and during use of this medication to adjust the dosage appropriately. In cases of overdose, procedures such as removing the drug from the gastrointestinal tract and clinical monitoring such as ECG tests should be performed; if necessary, hemodialysis may be used to remove the drug. This medication is unlikely to have significant interactions with other drugs, but caution is needed when taking specific medications, so inform your doctor or pharmacist.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• rash
• Stevens-Johnson syndrome
• cutaneous vasculitis
• exfoliative skin disease
• severe allergic reactions
• acute pancreatitis
• elevated liver enzymes

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• itching
• diarrhea

Store this medication in a tightly sealed container to protect it from air and moisture, and keep the storage temperature between 1°C and 30°C at room temperature. This will help maintain the medication's efficacy and prevent degradation.

Appearance

Round, biconvex, film-coated tablets with a light beige color

Package unit

Company packaging unit