Hyuniz Roxithromycin Tablets

Adult dose

(Tablets) Adults: Administer 150㎎ (potency) of roxithromycin per dose orally twice daily before breakfast and dinner. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose as appropriate according to age and symptoms.

Child dose

(Pediatric tablets)(Granules)(Suspension) Children: The average dose used in clinical trials was 6mg (potency) per Kg of body weight per day. Administer 5～8mg (potency) per Kg of body weight per day orally in 2 divided doses. Doses according to body weight are as follows. For children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 2.5mL per dose twice daily before meals (suspension only). For children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 5mL per dose twice daily before meals (suspension only). For children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 10mL per dose twice daily before meals (suspension only).

This medication can rarely cause serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. If you experience symptoms such as blistering of the skin or progression of mucosal damage, you should immediately discontinue the use of this medication. This medication should not be administered to those who are allergic to macrolide antibiotics or those currently taking specific drugs. Especially when taken with medications that can affect blood vessels or the heart, such as terfenadine, astemizole, cisapride, pimodzad, ergot alkaloids, and mizolastine could present risks. Patients with impaired liver function or the elderly should use caution when taking this medication, and it may lead to resistance or side effects when used concurrently with other antibiotics, thus consultation with a healthcare professional is recommended. This medication can impact heart rhythm, so individuals with congenital heart rhythm abnormalities or at risk of arrhythmias should consult a doctor before taking it. Additionally, patients with myasthenia gravis should be cautious as their symptoms may worsen when taking this medication. It is advised to monitor for allergic reactions, fever, rash, blood abnormalities, liver function anomalies, digestive upset, diarrhea, severe abdominal pain, breathing difficulties, dizziness, hearing impairment, and visual disturbances while taking this medication. If any of these symptoms occur, report to healthcare personnel immediately. Severe diarrhea or blood in stools may indicate pseudomembranous colitis; discontinue immediately and visit a hospital. This medication may interfere with the metabolism of various drugs in the liver, so interactions may arise when taken with other medications. Always inform your healthcare providers of any medications you are taking, as some should not be used together. Women who are pregnant or may become pregnant should only use this medication when the benefits to the mother outweigh the risks to the fetus, and breastfeeding should be discontinued if using this drug. The elderly may have increased drug concentrations, but typically do not require dosage adjustments. Dizziness or blurred vision can affect the ability to operate machinery or drive, so caution is advised. Finally, this medication should be stored out of reach of children, and transferring it to another container may decrease its quality, hence it is safest to keep it in the original container.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, fever, rash, allergic skin reaction, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, loss of appetite, nausea, vomiting, gastrointestinal discomfort, abdominal pain, abdominal distension, diarrhea, pseudomembranous colitis, loose stools, hemorrhagic colitis, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue paralysis, paralysis, taste disturbance, ageusia, olfactory disturbance, anosmia, erythema multiforme, purpura, superinfection due to excessive growth of non-susceptible pathogens, transient hearing loss, auditory impairment, visual impairment, blurred vision, conjunctival congestion, general malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of oral and vaginal mucosa, hallucinations, confusion

This medication should be stored in a tightly closed container to avoid exposure to air and moisture, and it is safest to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain its effectiveness and prevent degradation.

Appearance

White, round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle