Medication info
Astein Tablet 20 mg (Atorvastatin Calcium Hydrate)

Astein Tablet 20 mg (Atorvastatin Calcium Hydrate)

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Hydrate›21.7mg / 1 tablet
Manufacturer / importer
(주)경보제약
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201501997 · Approved 2015.04.13 · Insurance code 665001930

Summary

Main use
Reduction of risk of myocardial infarction and stroke, improvement of high cholesterol
Who uses it
Adults · Children
Adult dosage
The recommended initial dose for hyperlipidemia is 10 mg of atorvastatin once daily, but for patients requiring greater reductions in LDL cholesterol levels, it may be started at 20 mg or 40 mg once daily. This medication is administered in a dosage range of 10 to 80 mg once daily. The dosage should be individualized based on therapeutic goals and responses, with lipid levels analyzed and adjusted within 2 to 4 weeks.
Children's dosage
The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 10 mg once daily, with a maximum recommended dose of 20 mg per day. The dosage should be adjusted at intervals of 4 weeks or more.

Ingredients

Manufacturer
(주)경보제약

Efficacy & effects

Reduction of risk of myocardial infarction and stroke, improvement of high cholesterol

  • Myocardial infarction
  • stroke
  • vascular surgeries
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication helps to reduce the risk of cardiovascular diseases. It lowers the risk of myocardial infarction and stroke and helps to prevent cardiovascular issues such as vascular surgeries and angina. Additionally, it reduces the risk of heart disease in patients with diabetes. It is also used to treat hyperlipidemia by lowering cholesterol and triglycerides while increasing good cholesterol (HDL), thereby improving blood lipid status. It is specifically applicable to pediatric patients with familial hypercholesterolemia to lower their risk of heart disease. Through these effects, it is used to improve cardiovascular health and reduce the risk of heart diseases.

Dosage and Administration

Adult dosage

The recommended initial dose for hyperlipidemia is 10 mg of atorvastatin once daily, but for patients requiring greater reductions in LDL cholesterol levels, it may be started at 20 mg or 40 mg once daily. This medication is administered in a dosage range of 10 to 80 mg once daily. The dosage should be individualized based on therapeutic goals and responses, with lipid levels analyzed and adjusted within 2 to 4 weeks.

Children's dosage

The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 10 mg once daily, with a maximum recommended dose of 20 mg per day. The dosage should be adjusted at intervals of 4 weeks or more.

Precautions

This medication may pose a risk of muscle problems; therefore, if symptoms such as muscle pain or muscle weakness occur, notify your doctor immediately. In particular, if muscle enzyme levels are elevated or myopathy is suspected, the use of this medication should be discontinued. Patients with liver function issues or active liver disease should not take this medication. Women who are pregnant or may become pregnant, as well as breastfeeding women, should not use this medication. Children under the age of 10 should not take this medication, and adolescents aged 10 and over should take it under a doctor's guidance. Individuals with a history of alcohol abuse or liver disease should use this medication cautiously, and regular liver function tests are required. Elderly individuals have a higher risk of developing myopathy, so muscle condition should be carefully monitored when taking this medication. There are many interactions with other drugs, so caution is needed when taken with certain antibiotics, antifungals, antivirals, antihypertensives, antidiabetics, etc. Particularly, grapefruit juice can increase the blood concentration of this medication, raising the risk of side effects, so excessive intake should be avoided. If symptoms such as muscle pain, muscle weakness, fatigue, or fever occur, consult medical personnel immediately, and if necessary, perform blood tests to check muscle enzyme levels. It is important to regularly check liver function and muscle condition while taking this medication. For proper storage, keep it out of reach of children and store it in its original container.

Side effects and when to seek care immediately

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues associated with cough and fever, breathing problems, yellowing of skin or eyes (jaundice), extreme lethargy, liver issues (jaundice), sudden

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • fever
  • sinusitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
  • loss of appetite
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  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal/laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • dysgeusia
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent degradation.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.