Crebatin Tablet 10 mg (Rosuvastatin Calcium)

Adult dosage

For the treatment of primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia, the initial dose is 5 mg once daily. The maintenance dose is 10 mg once daily, which can be adjusted to a maximum of 20 mg daily at intervals of 4 weeks or more as needed. The medication can be taken at any time of the day regardless of meals.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), administer a dose once daily between 5 mg and 20 mg adjusted according to individual treatment goals. Dosing adjustments should occur every 4 weeks.

This medication may not be used in certain patients. For example, patients who are allergic to this drug, have severely impaired liver function, have muscle diseases, are taking certain medications with it, and women who are pregnant or breastfeeding should not take this medicine. Moreover, it is important to conduct repeated liver function tests and muscle-related tests before taking this medicine. Special caution should be exercised in individuals with a history of liver disease or high alcohol consumption, and any hypothyroidism should be treated prior to therapy. If symptoms of myalgia or muscle weakness occur, inform a physician immediately, and if necessary, discontinue the medicine. Severe muscle damage can lead to worsening renal failure, therefore, this drug should be discontinued in acute severe conditions. This drug may increase blood concentration when taken with certain medications, raising the risk of muscle damage; therefore, caution is required when used in combination with other drugs. Women who may become pregnant should use appropriate contraception and should not take this medication during pregnancy or while breastfeeding. In case of overdose, there is no specific antidote; therefore, symptomatic treatment and tests for liver function and muscle enzymes should be conducted. Dizziness may occur while taking this medicine, so caution should be exercised when driving or operating machinery. Finally, this medication may cause mild side effects such as headache, dizziness, myalgia, indigestion, etc., so if symptoms persist, consult a healthcare provider.

Serious side effects

Allergic reactions including urticaria, angioedema, Steven-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), hypersensitivity, severe allergic reactions, severe skin reactions, severe muscle weakness, rhabdomyolysis, fatal and non-fatal liver failure, liver abnormalities (jaundice), severe swelling or urination abnormalities, dyspnea, difficulty breathing, asthma attacks, severe chest tightness, shortness of breath

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• thrombocytopenia
• cough

This medicine may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 to 30 degrees Celsius at room temperature. This helps maintain the effectiveness of the drug over time.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle