Painless Sustained Release Tablet

Adult dose

Adjust the dosage according to the patient's level of pain and therapeutic response. Administer 1 tablet as the initial dose, with subsequent dosing intervals of at least 12 hours. Do not exceed 4 tablets per day, and avoid prolonged use beyond necessity. If prolonged use is needed due to the nature and severity of the disease, regular monitoring should be conducted. For elderly patients aged 75 and older, administer at intervals of at least 12 hours.

This drug may affect liver function, so individuals who regularly drink more than three alcoholic beverages a day should consult a doctor or pharmacist before taking it. One of the ingredients in this drug can rarely cause serious skin reactions, so if a rash or other allergic symptoms occur, discontinue use immediately. The main ingredient, tramadol, can increase the risk of seizures if taken in doses exceeding the recommended amount. Taking it with certain antidepressants or other central nervous system drugs may further increase the risk of seizures. Use with caution in patients with severe respiratory conditions, and administer in a location equipped with cardiopulmonary resuscitation equipment if necessary. Combining this drug with alcohol or benzodiazepines may result in severe drowsiness, respiratory depression, or coma, so such combinations should be avoided. Patients with head injuries or brain diseases should be cautious when using this drug, as respiratory suppression may increase intracranial pressure. This drug can cause psychological and physical dependence; therefore, long-term use requires careful monitoring for dependency and potential abuse. Patients with compromised liver function should consult a doctor before taking this medication due to the risk of liver damage. Particularly, patients with genetic variations affecting the metabolism of this drug may have an increased risk of respiratory suppression, requiring caution. This drug should not be administered to children under 12 years old or adolescents under 18 years old after certain surgeries, and adolescents between 12 and 18 years old should use it with caution. This drug can cause electrolyte imbalances known as hyponatremia, so elderly patients or those with risk factors should be closely monitored for symptoms. Patients with hypersensitivity to the ingredients or those on central nervous system drug detoxification, severe respiratory suppression, head injuries, or taking certain antidepressants should not take this medication. Pregnant or breastfeeding women should consult a doctor before taking this drug, and breastfeeding mothers should be especially cautious as the drug may be transmitted to the baby through breast milk. Drowsiness or dizziness may occur during driving or operating machinery, so caution is advised. Overdose may result in severe respiratory suppression or liver damage, so it is essential to strictly adhere to the dosage; in case of overdose, contact a medical institution immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision disturbances, paralysis, urination

Mild side effects

• Weakness
• fatigue
• flushing
• rigidity
• fainting
• withdrawal symptoms
• hypertension
• worsening hypertension
• hypotension
• arrhythmia

This drug should be stored in a sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and safety for a long time.

Appearance

Light yellow oblong sustained-release film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle