Medication info
Romantine Tablets (Memantine Hydrochloride)

Romantine Tablets (Memantine Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Memantine Hydrochloride›10mg / 1 tablet
Manufacturer / importer
(주)킵스바이오파마
Appearance
White rectangular film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201501639 · Approved 2015.03.27 · Insurance code 693201440

Summary

Main use
Treatment of moderate to severe Alzheimer's disease
Who takes it
Adults
Adult dose
This medication is to be taken orally once a day and should be administered at the same time every day. If necessary, it can be dosed twice daily. Adult dosage escalation: The maximum daily dose is 20 mg, and to minimize the risk of adverse reactions, it should be increased by 5 mg weekly for the first 3 weeks. - First week (days 1-7): Take 5 mg daily - Second week (days 8-14): Take 10 mg daily - Third week (

Ingredients

Manufacturer
(주)킵스바이오파마

Efficacy & effects

Treatment of moderate to severe Alzheimer's disease

  • Alzheimer's disease
View approved original text

This medication is used in the treatment of moderate to severe Alzheimer's disease.

How to take

Adult dose

This medication is to be taken orally once a day and should be administered at the same time every day. If necessary, it can be dosed twice daily. Adult dosage escalation: The maximum daily dose is 20 mg, and to minimize the risk of adverse reactions, it should be increased by 5 mg weekly for the first 3 weeks. - First week (days 1-7): Take 5 mg daily - Second week (days 8-14): Take 10 mg daily - Third week (

Precautions

This medicine should not be used in patients who are hypersensitive to its components, have severe liver dysfunction, or have severe renal impairment. It should be administered with caution in patients with epilepsy, those with a history of seizures, and individuals who are predisposed to epilepsy, as the risk of adverse effects may increase when combined with certain medications. Close monitoring is also required for patients at risk of factors that increase urinary acidity (pH), those with recent myocardial infarction, congestive heart failure, or uncontrolled hypertension. While taking this medication, adverse effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur; if symptoms worsen, consultation with healthcare professionals should be sought. There may be interactions with other medications, especially when used concurrently with NMDA antagonists, antipsychotics, skeletal muscle relaxants, and anticoagulants, so it is essential to consult with a doctor or pharmacist. Women who are pregnant or of childbearing potential should carefully consider the risks and benefits of using this medication, and breastfeeding women are advised to discontinue breastfeeding if taking this medication. For pediatric and adolescent patients under the age of 18, it is recommended not to use this medication as its safety and efficacy have not been established. In cases of overdose, symptoms of central nervous system distress and gastrointestinal symptoms may occur, so immediate medical attention should be sought for appropriate treatment. This medication may affect a patient's responsiveness, thus caution is advised when driving or operating machinery, and it should be kept out of reach of children. Additionally, transferring the medication to another container can lead to incidents, so caution is advised.

Side effects and when to seek care immediately

Serious side effects

  • Seizures
  • psychotic reactions
  • hallucinations
  • coma
  • convulsions
  • stupor
  • unconsciousness

Mild side effects

  • Dizziness
  • headache
  • constipation
  • drowsiness
  • hypertension
  • confusion
  • hallucinations
  • psychotic reactions
  • balance disorders
  • gait abnormalities
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  • seizures
  • heart failure
  • venous thrombosis/thromboembolism
  • dyspnea
  • vomiting
  • pancreatitis
  • elevated liver function test values
  • hepatitis
  • fatigue
  • restlessness
  • psychosis
  • visual hallucinations
  • stupor
  • unconsciousness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, at room temperature between 1 to 30 degrees Celsius. Storing it this way can help maintain its effectiveness for a longer time.

Appearance and packaging

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.