Clarithromycin 250 mg Tablet

Adult dosage

Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment period is 7～14 days. For patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer this medicine to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used by patients who are allergic to certain ingredients or have had hypersensitivity reactions. It should particularly be avoided in patients with heart rhythm problems or severely impaired liver and kidney function. It is also safer for pregnant or breastfeeding women not to take this medication. Serious side effects or drug interactions may occur when taken with certain other medications, so it is essential to inform your doctor or pharmacist of any medications you are currently taking. Elderly patients or those with weak liver or kidney function should adjust the dosage or use the medication with caution. If allergic reactions, severe skin rashes, breathing difficulties, or cardiac symptoms appear while taking this medication, discontinue use immediately and consult medical personnel. Additionally, various side effects such as gastrointestinal distress, liver function abnormalities, kidney function anomalies, and central nervous system symptoms can occur, so changes in symptoms should be monitored closely during treatment. Prolonged or high-dose use may cause tinnitus or hearing loss, so if these symptoms arise, promptly inform medical personnel. It’s important to use this antibiotic only for the required duration to prevent the development of antibiotic-resistant bacteria, and continue usage for the duration prescribed by your doctor even if symptoms improve. Lastly, as this medication contains lactose, patients with lactose intolerance should consult a specialist before use.

Shock, anaphylactic symptoms, shortness of breath, convulsions, flushing, rash, itching, urticaria, skin flush, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral erosion, upper abdominal pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, stool discoloration, membranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory impairment, tinnitus, hearing impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle spasms, musculoskeletal stiffness, myopathy, elevated blood urea, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration, vasodilation, angioedema, angioedema, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, diaphoresis, rash, urticaria, papular rash, acne, Henoch-Schonlein purpura

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is advisable to store the medication at room temperature, between 15 to 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained for a longer period.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle