Eurothera Tablet 10mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food. Swallow it whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment No dosage adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dosage adjustment is necessary for patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh Class B), and do not exceed 5mg once daily. 3. Patients receiving potent cytochrome P450 3A4(CYP3A4) inhibitors For patients receiving ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with urinary retention symptoms, severe gastrointestinal disorders, severe myasthenia gravis, or angle-closure glaucoma. Additionally, it should not be administered to those with allergies to this drug or its components, patients undergoing hemodialysis, severe liver impairment, and certain patients with severe kidney impairment taking specific medications. As it contains lactose, patients with lactose intolerance or related genetic disorders should not take it. Caution is advised when used in patients at risk of urinary retention, gastrointestinal obstruction, or reduced motility, and dosage should be limited in patients with impaired kidney or liver function. Common side effects of this medication may include dry mouth, constipation, blurred vision, urinary retention, and dry eyes; particularly, adverse reactions may be more frequent at high doses. If serious allergic reactions such as angioedema or anaphylaxis occur, administration should be stopped immediately, and appropriate treatment should be provided. This medication may cause blurred vision, drowsiness, and fatigue, so caution is needed when driving or operating machinery. Furthermore, when used with other anticholinergic medications, effects may be enhanced or side effects may worsen, so care should be taken during co-administration. As this drug is metabolized by specific liver enzymes (CYP3A4), dosage adjustments may be necessary when taken with drugs that strongly inhibit or induce this enzyme. The safety for pregnant women is not certain, so pregnant individuals should use it cautiously, and breastfeeding women are advised to avoid using this medication. Safety in children has not been established, so it should not be administered to children. In case of overdose, appropriate measures such as administering activated charcoal should be taken, and if severe central nervous system symptoms, heart issues, or urinary retention occur, immediate medical attention should be sought.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• nausea
• indigestion
• upper abdominal pain
• vomiting
• urinary tract infection

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain an ambient temperature between 1 to 30 degrees Celsius. This will help to preserve the medication's efficacy for a longer time.

Appearance

Bright pink, round, film-coated tablets

Package unit

100 tablets/box [10 tablets/PTP×10], 30 tablets/bottle, 100 tablets/bottle