Metformin Tablets 500mg (Metformin Hydrochloride)

Adult dose

The dosage must be determined individually based on the drug's efficacy and tolerance, and should not exceed the recommended maximum daily dose. This medication should always be started at a low dose to reduce gastrointestinal side effects and to determine the minimum effective dose for proper blood sugar control, and should be taken 500mg during meals 2-3 times a day. The dosage should be gradually increased by 500mg each week, reaching a total of 20

Child dose

Children over 10 years or adolescents are administered 500mg once daily during or after meals. Blood sugar levels should be measured after one week to adjust the dosage, and gastrointestinal side effects may gradually improve.

This medication may cause serious side effects such as severe lactic acidosis or hypoglycemia, so caution is needed. It should not be given to patients with moderate to severe renal impairment or those in acute conditions such as dehydration, severe infections, or acute myocardial infarction. In patients with acute and unstable heart failure, as well as before and after examinations using iodine contrast agents, this medication should be discontinued, and re-administration can only occur after kidney function has recovered to normal. It is not to be used in patients who have had allergic reactions to this medication or similar drugs, in type 1 diabetes patients, or in patients with a history of lactic acidosis or diabetic ketoacidosis. It should be used with caution in patients with severe infections, severe trauma, pre- and post-surgery, malnutrition, or liver or lung dysfunction, and administration should be temporarily stopped if necessary. This medication contains lactose, so it should not be given to patients with lactose intolerance or related genetic conditions. Caution is also required in cases of irregular meals, excessive exercise, or interactions with other medications, which may increase the risk of hypoglycemia or lactic acidosis. Lactic acidosis, though rare, can be fatal, so any symptoms such as malaise, muscle pain, shortness of breath, or abdominal pain should be immediately reported to medical personnel. Gastrointestinal disturbances are common at the initiation of treatment but are usually temporary and can be alleviated by taking the medication with meals or gradually increasing the dosage. Blood sugar control status should be regularly monitored, and kidney function and hematological values should be consistently monitored. Alcohol may increase the risk of side effects from this medication, so excessive drinking should be avoided. During pregnancy, it may affect the fetus, so it is essential to consult a physician if planning to become pregnant or during pregnancy, and it should not be administered if there is a risk of placental insufficiency or preeclampsia. During breastfeeding, as this medication may be secreted in breast milk, careful consideration should be given to whether to continue nursing or stop medication. In elderly patients, kidney function may decline, so dose adjustment and regular kidney function tests are necessary, and it is advisable not to administer the maximum dosage. In cases of overdose, the drug can be removed through hemodialysis, so if overdose occurs, medical attention should be sought immediately. This medication may interact with other hypoglycemic agents or multiple medications, so it is essential to inform medical personnel of any concurrent medications and closely monitor blood sugar and the patient's condition. Finally, this medication should be kept out of reach of children, and care should be taken not to transfer it to other containers as this may affect its quality.

Serious side effects

Lactic acidosis, severe allergic reactions (rash), hypoglycemia, liver abnormalities (possible liver function impairment)

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain), metallic taste, anemia, leukopenia, thrombocytopenia, vitamin B12 deficiency, liver function abnormalities, severe delayed hypoglycemia

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is important to store it at room temperature, specifically between 1 degree and 30 degrees Celsius, to maintain its effectiveness.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle