Celtis Pamotidine Tablet 20 mg (Pamotidine)

Adult dosage

Oral administration: 1. For gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: take 20 mg per dose, twice daily (after breakfast, after dinner, or at bedtime) or 40 mg per dose, once daily (at bedtime). 2. For the improvement of gastric mucosal lesions during the acute exacerbation of acute and chronic gastritis: take 10 mg per dose, twice daily or 20 mg per dose, once daily (at bedtime).

This medication should not be used by patients who are allergic to specific ingredients or have hypersensitivity to H2 receptor antagonists. Additionally, it contains lactose, so individuals with lactose intolerance or related genetic disorders should not take it. Patients with hypersensitivity to the medication or those with problems in renal, liver, or cardiac functions, as well as the elderly, should take this medication with caution. This medication may rarely cause severe allergic reactions or abnormalities in blood, skin conditions, liver dysfunction, muscle injury, heart rhythm problems, kidney issues, or consciousness disturbances, so conditions should be carefully monitored. If such adverse symptoms occur, discontinue the medication immediately and consult a healthcare professional. Common side effects may include skin rash, dyspepsia, blood pressure changes, respiratory issues, and neurological symptoms. During treatment, closely observe any changes in symptoms, use the minimum effective dose, and switch to other treatments if there is no efficacy. This medication dissolves in the mouth but is not absorbed through the oral mucosa; therefore, it must be swallowed with water or saliva. Patients undergoing dialysis should be cautious as the effectiveness of this medication may decrease when used with phosphate binders. Taking this medication with certain antifungals or some anticancer drugs may reduce the efficacy, so patients should inform healthcare professionals about any medications they are currently taking. Elderly individuals may have reduced kidney function, which may require dose adjustment or interval modification. Pregnant women or those who may become pregnant should only use this medication if the benefits outweigh the risks, and breastfeeding mothers are advised to discontinue breastfeeding as the drug may be transmitted through breast milk. Safety has not been fully established in children, so caution is advised when using this medication. Lastly, this medication may conceal symptoms of gastric cancer, so it should only be used after confirming the malignancy status.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, systemic flushing, angioedema including facial swelling and pharyngeal swelling, urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia (general fatigue, weakness, subcutaneous or mucosal bleeding, fever, etc.), Stevens-Johnson syndrome, Lyell's syndrome, liver dysfunction, jaundice, rhabdomyolysis (hyperkalemia, myoglobinuria, elevated serum muscle enzymes, myalgia), QT prolongation.

Mild side effects

• Rash
• redness (erythema)
• facial swelling
• constipation
• diarrhea
• thirst
• nausea
• vomiting
• abdominal bloating
• loss of appetite

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1°C and 30°C. Proper storage can help maintain the medication's efficacy for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle