Omecle Neo Syrup (Amoxicillin Hydrate - Potassium Clavulanate)

Adult dose

The experience of using this medicine in adults is lacking. To minimize the possibility of gastrointestinal disturbance, this medicine is administered at the beginning of meals. When administered at the beginning of meals, the absorption of potassium clavulanate is increased.

Child dose

Children over 3 months: The dosage is based on amoxicillin content (600 mg/5 mL) at 90 mg/kg/day divided into doses every 12 hours, with 10 days for acute otitis media and 7 days for acute sinusitis.

This medicine contains the artificial sweetener aspartame, so patients with phenylketonuria should not take this medicine. The intake of aspartame should be minimized to not exceed the recommended amount by WHO, and in the case of a 60 kg adult, it should not exceed 2.4g per day. Patients with hypersensitivity to any ingredients of this medicine or beta-lactam antibiotics should not take this medicine, and particularly, patients with infectious mononucleosis or lymphocytic leukemia should avoid it due to the risk of skin rash. Patients who have experienced liver dysfunction or jaundice in the past due to this medicine or penicillin should not be administered as there is a risk of recurrence. This medicine contains lactose, so it should not be administered to patients with lactose intolerance, galactose intolerance, or glucose-galactose malabsorption. Patients with impaired liver function should use this medicine with caution, and for those with moderate to severe renal impairment, the dosing interval should be extended. Patients with a history of allergies or those with easily appearing symptoms such as bronchial asthma, skin rashes, or urticaria should use this medicine with caution. Patients who have difficulty with oral intake, elderly patients, or those in poor condition should be careful as vitamin K deficiency symptoms may occur. Patients with digestive diseases accompanied by vomiting or diarrhea should be cautious as the medication may not be properly absorbed. Generally, this medicine has good tolerability, but side effects such as contact dermatitis, diarrhea, vomiting, rashes, etc. may occur, and in severe cases, administration should be stopped. Gastrointestinal side effects may include diarrhea, gastritis, vomiting, abdominal pain, with a higher incidence in infants under 2 years old. Liver function abnormalities may rarely occur and are more frequent in the elderly or males, so regular monitoring of liver function is recommended. Allergic reactions may feature itching, skin rashes, and in severe cases, serious skin reactions such as Stevens-Johnson syndrome, so immediate consultation with medical personnel is necessary if symptoms arise. Hematologic abnormalities such as leukopenia, thrombocytopenia, and hemolytic anemia have been rarely reported; any abnormal symptoms should be confirmed. Neurological abnormalities may include anxiety, confusion, seizures, and more caution is needed in patients with reduced renal function. Renal adverse reactions of acute renal failure or nephritis may occur, necessitating regular renal function tests. This medicine may affect the intestinal flora, potentially leading to fungal infections like candidiasis. Long-term use may lead to vitamin K deficiency symptoms, so caution is advised for patients with bleeding tendencies. As an antibiotic, this medicine is ineffective against viral infections, and even if symptoms improve during treatment, it is essential to continue taking it for the prescribed duration. The solution must be shaken well before use, stored in the refrigerator after preparation, and used within 7 days. Pregnant women or those who may become pregnant should particularly avoid taking this medicine during the first trimester, and caution should be exercised while breastfeeding, as it may cause adverse effects in infants. This medicine should not be used in pediatric patients, especially infants under 3 months, as safety and efficacy have not been established. There may be interactions with other medications, so patients should inform their healthcare provider if they are taking any other medications, particularly with anticoagulants or certain antibiotics. In cases of overdose, gastrointestinal symptoms, renal damage, and seizures may occur, requiring immediate medical attention. This medicine should be kept out of reach of children and stored in a dry place below 25 degrees Celsius. Patients should follow the doctor's instructions accurately and consult medical personnel immediately if any abnormal symptoms appear.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash accompanied by high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough + fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urine changes

Mild side effects

Contact dermatitis, diarrhea, vomiting, moniliasis, rash, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, black hairy tongue, nausea, anorexia, abdominal pain, abdominal distention, constipation, colonic pain, hyperacidity, loose stools, dry mouth, candidiasis, cholestatic jaundice, hepatitis, itching, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, vesicular exfoliative dermatitis, acute generalized exanthematous pustulosis, eosinophilia, serum sickness, overdose

This medicine is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it should be kept in a cool, dry place between 1 to 25 degrees Celsius to maintain its efficacy.

Appearance

A syrup preparation in the form of a white to light yellow powder with a distinctive odor that is dissolved before use.

Package unit

50 mL/bottle