Cero-Cap 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, consider another treatment option. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding in individuals who consume large amounts of alcohol daily, and consultation with a doctor or pharmacist is required. Individuals with heart or vascular issues or risk factors should use this medication only at the minimum dose and for a short duration, as it may induce cardiovascular problems such as myocardial infarction and stroke; symptoms must be reported immediately. People with a history of ulcers or bleeding in the stomach, especially the elderly, need to be cautious, as this medication increases the risk of gastrointestinal perforation or bleeding. This medication should not be used by individuals with certain allergic reactions, severe liver or kidney diseases, heart disease, those who are pregnant or breastfeeding, or those with specific genetic disorders. Individuals with impaired liver or kidney function, asthma, hypertension, edema, heart failure, diabetes, or blood coagulation disorders should use this medication carefully and undergo regular examinations as necessary. Dizziness or drowsiness may occur during use, so it is advisable to avoid driving or operating machinery. This medication may interact with other drugs; therefore, it is essential to consult a professional when taken together with medications such as antihypertensives, anticoagulants, diuretics, or antidepressants. Women who are pregnant or planning to become pregnant should consult a doctor before use, as this medication may affect fertility, and it should be avoided during pregnancy. Long-term use of this medication requires regular blood tests as well as liver and kidney function checks to detect abnormal signs early. Overdose can result in nausea, vomiting, drowsiness, gastrointestinal bleeding, etc., requiring immediate hospital treatment. Safety and efficacy for children and adolescents under 18 have not yet been established, so it is advisable not to use this medication. Keep this medication out of reach of children and do not transfer it to other containers for safety.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory loss, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, jaundice, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon ruptures, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, gustatory dysfunction, albuminuria, cystitis, hematuria, dysuria, increased urinary frequency, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, acute renal failure, interstitial nephritis

This medication should be stored in a tightly sealed container to prevent air and moisture. Additionally, it is best kept at room temperature between 15 to 30 degrees Celsius to maintain its efficacy.

Appearance

A white to pale yellow powder-filled capsule with white upper and lower parts and yellow bands.

Package unit

30 capsules/bottle, 100 capsules/bottle