Coxib Capsule 100mg (Celecoxib)

Adult dose

The minimum recommended dose of this medication should be adjusted according to the patient and may be taken with or without food. Osteoarthritis (degenerative joint disease): Take celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to up to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, another treatment option should be considered. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose as needed is 200 mg twice daily. For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic beverages per day, so consultation with a doctor or pharmacist is mandatory. This medication can increase the risk of serious cardiovascular side effects such as thrombotic events, myocardial infarction, and stroke, and should only be used at the minimum effective dose and for the shortest duration necessary. If symptoms such as chest pain, shortness of breath, weakness, or speech disturbances occur during treatment, immediate consultation with medical staff is required. This medication may increase the risk of gastrointestinal events such as perforation, ulcers, and bleeding, so immediate evaluation and treatment are needed if symptoms like epigastric pain, indigestion, black stools, or hematemesis occur. Elderly patients or those with a history of gastrointestinal disorders require special caution due to an increased risk of gastrointestinal adverse reactions when taking this medication. This medication is not to be administered to individuals with a history of specific allergies or severe liver, kidney disorders, active peptic ulcers, heart failure, or pregnant women. Patients with reduced liver or kidney function, hypertension, heart failure, asthma, etc., require careful monitoring while taking this medication. During treatment, various adverse reactions such as headache, dizziness, indigestion, skin rash, edema, hypertension, and cough may occur, and should symptoms persist or worsen, consultation with a doctor is necessary. This medication is metabolized in the liver, so caution is needed when co-administered with other drugs that affect liver metabolism as it may alter blood concentration levels. Women who are pregnant or could become pregnant should not take this medication, and breastfeeding women should consult a doctor if considering its use. The safety and efficacy of this medication in children and adolescents under 18 years of age have not been established, so its use is not recommended. Elderly patients have a higher likelihood of decreased kidney, liver, and heart function, thus require more careful monitoring while taking this medication. Patients taking this medication for an extended period should undergo regular blood tests and liver and kidney function tests to detect any abnormalities early. In case of overdose, symptoms such as lethargy, drowsiness, nausea, vomiting, and gastrointestinal bleeding may occur, requiring appropriate treatment based on the symptoms. This medication should be kept out of the reach of children, and transferring to another container should be avoided. During treatment, dizziness or drowsiness may occur while driving or operating machinery, so caution is advised.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, liver enzyme elevation, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, tension, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergy, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, angioedema, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease nephritis, menstrual disorders, female infertility, chest pain, vesicular dermatitis, nail disease, photosensitivity reactions, dermatitis, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucosal syndrome, toxic epidermal necrolysis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequency of urination, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, impaired kidney function, acute renal failure, interstitial nephritis, peptic ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, shortness of breath, ALT elevation, hearing loss, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell

This medication should be stored in a well-sealed container to prevent air or moisture from entering. Additionally, to maintain the effectiveness of the medication, it is best kept in a cool place between 15 to 30 degrees Celsius.

Appearance

Capsule filled with a white to light yellow powder, with a blue top and white bottom

Package unit

30 capsules/bottle, 300 capsules/bottle