Selconazole 100 mg (Itraconazole)

Adult dose

This drug should preferably be administered immediately after meals to increase absorption. 1. Short-term treatment This drug continues to exert a therapeutic effect in skin tissue even after discontinuation. Therefore, it is advisable to assess the final clinical and mycological response 2～4 weeks after completion of the prescribed treatment. 1) Candida vaginitis: Administer itraconazole 200 mg per dose twice daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. 2) Tinea versicolor: Administer 200 mg once daily for 7 days. 3) Tinea corporis and tinea cruris: Administer 100 mg once daily for 15 days. 4) Tinea of the hands (interdigital) and tinea of the feet (interdigital): Administer 100 mg once daily for 15 days. 5) Tinea of the hands (palms) and tinea of the feet (soles): Administer 100 mg once daily for 30 days or 200 mg per dose twice daily for 7 days. 6) Oral candidiasis: Administer 100 mg once daily for 15 days. 7) Fungal keratitis: Administer 200 mg once daily for 21 days. 2. Onychomycosis 1) Pulse therapy Administer 200 mg per dose twice daily for 1 week, followed by a 3-week drug-free period; this constitutes 1 cycle. Administer up to 2 cycles for infection of the fingernails only and up to 3 cycles for infection of the toenails. Toenails (with or without concomitant fingernail infection): 1 week on treatment, 2 weeks off treatment, 3 weeks on treatment, 4 weeks off treatment, 5 weeks on treatment Fingernails: 1 week on treatment, 2 weeks off treatment, 3 weeks on treatment 2) Continuous therapy Administer 200 mg once daily for 3 months. The therapeutic effect continues for 3 months for fingernails and 6 months for toenails after the end of treatment. 3. Systemic fungal infections In patients with impaired immune function, such as those with neutropenia, AIDS, or organ transplant recipients, the oral bioavailability of this drug may be reduced; if necessary, increase the dose twofold. Aspergillosis: 200mg once daily; average treatment duration 2～5 months. For invasive or disseminated disease, increase to 200mg per dose twice daily. Candidiasis: 100～200mg once daily; average treatment duration 3 weeks～7 months Cryptococcal meningitis: 200mg twice daily; average treatment duration 2 months～1 year. Maintenance therapy: 200mg once daily Paracoccidioidomycosis: 100mg once daily; average treatment duration 6 months

This medication may be life-threatening for patients with impaired cardiac function, especially those with congestive heart failure, and should not be used unless absolutely necessary. If symptoms of heart failure occur during use, administration should be stopped immediately. Patients with hypersensitivity or a history of allergies to this medication should not use it. Since this drug is mainly metabolized in the liver, patients with impaired liver function should use it cautiously and have regular liver function tests. Patients with poor kidney function may also require dosage adjustment, so they should follow their physician's instructions. It is safest for women who are pregnant or may become pregnant, and those who are nursing, to avoid using this drug. This medication can interact with many other drugs, so be sure to inform your healthcare provider about any other medications you are taking, especially when used with heart medications, analgesics, antibiotics, anticoagulants, antipsychotics, and anticancer drugs. During treatment with this medication, unusual symptoms such as dizziness, headache, dyspepsia, skin rash, and hearing impairment may occur, and if these symptoms arise, you should consult your healthcare provider immediately. Use cautiously in children and the elderly, and monitor their condition closely before and after administration. There is no specific antidote for overdose; treatment should be symptomatic, and it is not removed by hemodialysis. This medication should be kept out of reach of children and stored in the original container to maintain quality.

Headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory infection, leukopenia, hypersensitivity, taste disorder, sensory impairment, sensory abnormality, tinnitus, constipation, diarrhea, indigestion, bloating, vomiting, abnormal liver function, hyperbilirubinemia, pruritus, rash, urticaria, frequent urination, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusion, peripheral neuropathy, dizziness, drowsiness, tremor, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, speech disorder, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, renal impairment, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, increased alanine aminotransferase, increased aspartate aminotransferase, increased serum alkaline phosphatase, increased serum lactate dehydrogenase, increased blood urea, increased gamma-glutamyl transferase, increased liver enzymes, abnormal urinalysis, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioneurotic edema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, transient hearing loss, permanent hearing loss, ventricular ectopic beats, atrial block, palpitations, increased intestinal motility, belching, glossitis, stomatitis, abdominal and lower back pain, pancreatitis, increased total serum protein, elevated total bilirubin, increased LAP, decreased appetite, malaise, brown urine, mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Richelieu syndrome, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, elevated BUN, positive urine protein, positive urine glucose, decreased libido, drowsiness, malaise, shoulder stiffness, insomnia, chest pain, elevated serum triglycerides, burning sensation, elevated serum uric acid, elevated serum potassium, serum sickness, angioneurotic edema, anaphylactic reaction, hyperlipidemia, tremor, visual impairment, congestive heart failure, dyspnea, pancreatitis, severe hepatotoxicity, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, erythema multiforme, exfoliative dermatitis, leukocytoclastic vasculitis, hair loss, photosensitivity, increased serum creatine phosphokinase activity

This medication should be stored in a tightly closed container to prevent air from entering, at room temperature between 1°C and 30°C. Proper storage will help maintain the drug's effectiveness for a longer time.

Appearance

White to off-white oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle