Crestin Tablet 20mg (Rosuvastatin Calcium)

Adult dose

For primary hypercholesterolemia, mixed dyslipidemia, and primary dysbetalipoproteinemia, the medication can be taken at any time during the day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is 10 mg once daily; most patients are adjusted to this dosage. The maintenance dose should be adjusted every 4 weeks or more based on LDL cholesterol levels, therapeutic goals, and patient response.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), the dose is given once daily from 5 mg to 20 mg. The dosage should be adjusted according to the therapeutic goals of the individual patient.

It is very important not to use this medication in certain patients. For example, individuals allergic to any component of this medication or with severe liver dysfunction or muscle disorders should not take it. Additionally, those with significantly impaired kidney function or women who are pregnant or breastfeeding should also avoid using this medication. This drug carries a risk of causing muscle problems, hence caution is necessary in patients with a history of muscle disorders or those taking certain medications concurrently. Individuals with genetic issues such as lactose intolerance should not take this medication. Those who consume alcohol heavily or have liver disease should undergo multiple liver function tests before taking this medication. If symptoms such as muscle pain or weakness occur, inform a doctor immediately, and the medication may need to be discontinued as necessary. Furthermore, this medication should be discontinued after severe renal failure, infections, or major surgeries. It can rarely cause severe skin reactions or liver dysfunction, so if symptoms like skin rashes or jaundice occur, it should be stopped immediately. Interactions may occur when taken with other medications, so it is crucial to inform the doctor or pharmacist about any concurrent drugs. Women of childbearing potential should use appropriate contraception and stop taking the medication immediately if they become pregnant. In case of overdose, no specific antidotes are available, thus treatment is based on symptoms, and monitoring of liver function and muscle enzyme levels is essential. Dizziness may occur when driving or operating machinery, so caution is advised. This medication may show higher blood concentrations in Asians, so dose adjustments may be necessary. Overall, this medication can impact liver and muscle health, so regular check-ups and symptom monitoring are important.

Serious side effects

Allergic reactions including urticaria and angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with fever, blistering, skin peeling, mucosal pain in mouth/eyes, severe skin adverse reactions, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), shortness of breath or difficulty breathing, asthma attacks, cough plus fever

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• fatigue
• numbness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to store the medication at room temperature between 1 to 30 degrees Celsius.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle