Solifenacin Tablet 10 mg (Solifenacin Succinate)

Adult dose

The recommended dose for adults (including the elderly) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken without regard to meals and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dose adjustment is necessary for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use caution in patients with severe renal impairment (creatinine clearance≤30ml/min) and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dose adjustment is necessary for patients with mild hepatic impairment. Use caution in patients with moderate hepatic impairment (Child-Pugh class B) and do not exceed 5mg once daily. 3. Patients receiving potent cytochrome P450 3A4 (CYP3A4) inhibitors: For patients receiving ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used by certain patients. For example, individuals who have trouble urinating, those with serious gastrointestinal issues, patients with severe muscle weakness, glaucoma patients with eye problems, anyone allergic to this medication or its components, patients undergoing hemodialysis, and those with very poor liver or kidney function should not use this medication. Also, caution should be taken when using this medication in patients with bladder outlet obstruction risk or gastrointestinal obstruction, those at risk for decreased gastrointestinal motility, patients with slightly poor liver or kidney function, and those taking certain other medications. Common side effects may include dry mouth, constipation, blurred vision, urinary retention, dry eyes, nausea, indigestion, upper abdominal pain, vomiting, urinary tract infections, influenza, pharyngitis, dizziness, depression, lower extremity edema, fatigue, cough, high blood pressure, difficulty urinating, reduced urinary flow, post-voiding sensation, cystitis, nasopharyngitis, vomiting, gastroesophageal reflux disease, headache, hallucination, drowsiness, delirium, kidney impairment, itching, rash, erythema multiforme, exfoliative dermatitis, atrial fibrillation, palpitations, tachycardia, and ECG changes. Caution is also needed in patients with arrhythmias or altered potassium levels as this medication may lead to cardiac rhythm issues. Additionally, care should be taken while driving or operating machinery during the course of treatment. While taking this medication alongside other anticholinergic drugs, effects may be heightened or side effects may worsen, so you must inform your doctor. Dosage adjustments may be necessary when used with certain antifungals or other medications. Pregnant women or breastfeeding mothers should consult with their doctor before taking this medication, and it is not to be used in children as safety has not been established. In the event of overdose, it is crucial to go to the hospital immediately for appropriate treatment, and do not induce vomiting. Finally, while this medication has been reported not to increase the risk of tumor formation with prolonged use, any abnormal symptoms during use should be discussed with a healthcare professional immediately.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioedema
• nausea

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Furthermore, it is advisable to keep the medication at room temperature between 1 to 30 degrees Celsius, avoiding extremely hot or cold places. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Bright pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle