Medication info
Oraloxacin Tablet 100 mg (Ofloxacin)

Oraloxacin Tablet 100 mg (Ofloxacin)

Prescription medicationTabletOral
Ingredient · strength
Ofloxacin›100mg / 1 tablet
Manufacturer / importer
Hankook Hutech Pharmaceutical Co., Ltd.
Appearance
White, round film-coated tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201405581 · Approved 2014.11.27 · Insurance code 649102580

Summary

Main use
Treatment of respiratory, otorhinolaryngologic, and skin and soft-tissue infections; genitourinary, intestinal, and eye infections; combination therapy for leprosy
Who takes it
Adults
Adult dose
The usual adult dose is 300~600 mg of ofloxacin daily, divided into 2~3 doses. For Hansen's disease, take 400~600 mg of this medicine daily, divided into 2~3 doses. In principle, use in combination with other anti-Hansen's disease drugs. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Hankook Hutech Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory, otorhinolaryngologic, and skin and soft-tissue infections; genitourinary, intestinal, and eye infections; combination therapy for leprosy

  • Complex skin and soft tissue infections
  • acute otitis media
  • chronic purulent otitis media
  • acute bacterial sinusitis
  • chronic bacterial sinusitis
  • community-acquired pneumonia
  • chronic bronchitis
  • acute exacerbations of chronic obstructive pulmonary disease
  • acute pyelonephritis
  • uncomplicated acute cystitis
  • bacterial prostatitis
  • epididymitis
View approved original text

This medication is effective against a variety of bacteria including Staphylococcus, Streptococcus, Escherichia coli, and Streptococcus pneumoniae. It is used to treat complex skin and soft tissue infections, acute and chronic otitis media, and acute and chronic sinusitis. It is also effective for acute exacerbations of chronic obstructive pulmonary disease including community-acquired pneumonia and chronic bronchitis. It is suitable for treating urinary tract infections, bacterial prostatitis, and intrauterine infections. This medication is used for infections around the eyes and corneal ulcers, and is particularly prescribed when there are no other treatment options. This medication should be used cautiously considering the potential for serious adverse reactions, and it is effective in treating various bacterial infections.

How to take

Adult dose

The usual adult dose is 300~600 mg of ofloxacin daily, divided into 2~3 doses. For Hansen's disease, take 400~600 mg of this medicine daily, divided into 2~3 doses. In principle, use in combination with other anti-Hansen's disease drugs. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication is a fluoroquinolone antibiotic used to treat specific bacterial infections. While taking this medication, serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, central nervous system effects, and exacerbation of myasthenia gravis may occur, so caution is advised. Patients with myasthenia gravis should not take this medication as it may worsen their symptoms. This medication should only be used for limited indications such as acute bacterial sinusitis, acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, uncomplicated urinary tract infections, and acute otitis media when there are no other treatment alternatives available. Elderly patients, those with renal impairment, solid organ transplant recipients, and those taking corticosteroids should avoid taking this medication along with corticosteroids due to a higher risk of tendon rupture. If tendon pain, inflammation, or rupture symptoms occur during treatment, discontinue the medication immediately and consult a doctor, as rest and limited activity may be necessary. This medication may increase the risk of seizures, so special caution is needed for patients with a history of epilepsy or central nervous system disorders. Hypersensitivity reactions such as rash, itching, and fever may occur, and if these symptoms arise, the medication should be discontinued immediately. This medication may affect renal and liver function, requiring regular monitoring and observation for long-term use. Gastrointestinal side effects such as nausea, vomiting, and diarrhea may occur, and patients should inform their doctor if these symptoms arise. Blood system abnormalities, neurological and psychiatric effects (insomnia, dizziness, hallucinations, etc.), skin reactions (Stevens-Johnson syndrome), musculoskeletal problems (myalgia, muscle weakness, etc.) have also been reported, so vigilance is necessary. Cardiovascular side effects may include changes in blood pressure, palpitations, and arrhythmias, so immediate medical attention should be sought for any abnormal symptoms. Diabetic patients should monitor their blood sugar levels carefully, as changes may occur while taking this medication. This medication may interact with certain drugs (anticoagulants, some anti-inflammatory drugs, antacids, etc.), so patients should inform their doctor or pharmacist prior to use and exercise caution during concurrent use. Women who are pregnant or may become pregnant, breastfeeding women, and adolescents under 18 years of age, as well as patients with certain disease histories, should avoid using this medication. Patients should avoid strong sunlight exposure during treatment, and if symptoms such as dizziness occur, they should refrain from driving or operating machinery. In case of overdose, immediate medical attention is required, and this medication is not fully removed by dialysis. Store this medication in a tightly closed container to prevent air exposure, and keep it at room temperature between 1 to 30 degrees Celsius. This helps maintain the medication's effectiveness.

Side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, worsening myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, erythema, edema, fever, warmth, vesicles, erythema, photosensitivity reactions, hematuria, acute kidney failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, abdominal pain, diarrhea, nausea, vomiting, gastric discomfort, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, dysgeusia, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechiae and purpura, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, neural hyperexcitability, sleep disturbances, confusion, anxiety, depression, agitation, lethargy, delirium, suicidal thoughts, suicide, perceptual disturbances, olfactory and vestibular sensory disturbances, ataxia, aphasia, heaviness in the head, Stevens-Johnson syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscular weakness, myositis, lack of strength, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, prolonged QT interval, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, vulvar itching in females, irregular menstruation, uterine cramps, genital rash in females, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever, aortic aneurysm, aortic dissection, valvular regurgitation, valvular insufficiency

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way helps preserve the medication's efficacy.

Appearance and packaging

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.