Rimaf Tablet (Rimiprost alpha-dex)

Adult dose

For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets per dose, 3 times daily orally. For improvement of subjective symptoms (lower limb pain and numbness) and walking ability due to acquired lumbar spinal stenosis (in patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet per dose, 3 times daily orally. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose, so it should not be administered to patients with genetic issues such as lactose intolerance, hereditary lactase deficiency, or glucose-galactose malabsorption. It should be used cautiously in patients with bleeding tendencies or those taking antiplatelet agents, thrombolytics, or anticoagulants. Allergic reactions such as skin rash or itching may occur with this medication, and if such symptoms arise, use should be stopped immediately. Bleeding may occur rarely, so if bleeding symptoms appear, discontinue use immediately and monitor. Gastrointestinal side effects such as diarrhea, nausea, abdominal pain, loss of appetite, and heartburn may occur, and in rare cases, vomiting or abdominal distension may also occur. Liver function abnormalities may occur, so it is advisable to regularly check liver enzyme levels (AST, ALT). Cardiovascular symptoms such as palpitations, hypotension, and peripheral cyanosis may also occur, so caution is required. Various other side effects including headache, facial flushing, dizziness, warmth, general malaise, edema, trembling, excess body hair, and anemia may occur, so symptoms should be closely monitored. In patients with lumbar spinal stenosis, symptoms should be observed carefully to decide whether to continue the medication. The efficacy of this medication as an alternative to surgery in severe cases of lumbar spinal stenosis has not been definitively proven. Safety during pregnancy has not been established, so pregnant women or those who may become pregnant should avoid this medication as uterine contraction effects have been reported in animal studies. Safety in children has not been confirmed, and experience in use is lacking, so caution is necessary. Elderly patients may have reduced physiological function, so careful dosage adjustment may be required. Administering this medication in large doses to healthy adults may temporarily lower blood pressure, so caution is required.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature between 1 degree and 30 degrees Celsius, avoiding very cold or very hot places.

Appearance

White round tablet

Package unit

84 tablets (21 tablets/PTP x 4)