Medication info
Rabehue Tablet 10mg (Rabeprazole Sodium)

Rabehue Tablet 10mg (Rabeprazole Sodium)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›10mg / 1 tablet
Manufacturer / importer
(주)휴비스트제약
Appearance
Pale yellow round enteric-coated tablet
Packaging
28 tablets (14 tablets/AluAlu packaging x 2)
Approval status
Active

MFDS item code 201405520 · Approved 2014.11.25 · Insurance code 628800480

Summary

Main use
Improvement of gastrointestinal diseases such as treatment of gastric ulcers and duodenal ulcers, alleviation of symptoms of gastroesophageal reflux disease.
Who takes it
Adults
Adult dose
For gastric ulcer and duodenal ulcer: Take 10 mg orally once daily. Depending on symptoms, 20 mg may be taken orally once daily. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg taken orally once daily for 4 to 8 weeks. If not resolved after 8 weeks of proton pump inhibitor therapy, an additional 8 weeks of 10 mg or 20 mg may be taken orally twice daily.

Ingredients

Manufacturer
(주)휴비스트제약

Efficacy & effects

Improvement of gastrointestinal diseases such as treatment of gastric ulcers and duodenal ulcers, alleviation of symptoms of gastroesophageal reflux disease.

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • gastroesophageal reflux disease
  • gastrointestinal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used in the treatment of gastric and duodenal ulcers, for alleviating symptoms of gastroesophageal reflux disease, and for long-term maintenance therapy. It is also used in combination with antibiotics for the treatment of gastrointestinal ulcers caused by Helicobacter pylori infection, and is effective for diseases characterized by excessive gastric acid secretion such as Zollinger-Ellison syndrome. These treatments help reduce damage caused by gastric acid and improve symptoms.

How to take

Adult dose

For gastric ulcer and duodenal ulcer: Take 10 mg orally once daily. Depending on symptoms, 20 mg may be taken orally once daily. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg taken orally once daily for 4 to 8 weeks. If not resolved after 8 weeks of proton pump inhibitor therapy, an additional 8 weeks of 10 mg or 20 mg may be taken orally twice daily.

Precautions

This drug should not be used in patients with allergies to certain medications or components. Women who are pregnant or breastfeeding should also avoid using this drug. Patients with impaired liver function or the elderly should use this drug with caution, and individuals with a history of allergies should also use it carefully. If allergic reactions such as skin rash or itching occur while taking this medication, discontinue use immediately. It is important to regularly undergo blood tests and liver function tests to check for abnormalities. Symptoms related to the heart or vascular system may occur, so if symptoms appear, consult a medical professional. Mental symptoms, neurological abnormalities, and respiratory symptoms may also occur, so caution is required. Long-term use may increase the risk of bone fractures and lead to electrolyte imbalances such as hypomagnesemia, hence regular monitoring is necessary. This drug strongly inhibits gastric acid secretion, which may slightly increase the risk of bacterial infections in the stomach. Caution is needed as drowsiness or dizziness may occur when driving or operating machinery. Since this drug may interact with other medications, inform your healthcare provider about any other medications you are taking. Do not chew or crush this drug; swallow it whole, and keep it out of the reach of children. There is no specific antidote for overdose; treatment should be symptomatic. Long-term use may result in impaired absorption of vitamin B12, so regular monitoring is required. If symptoms of autoimmune diseases such as systemic lupus erythematosus appear while taking this drug, discontinue use immediately and consult with a specialist. It is recommended to discontinue this medication at least 14 days prior to measuring serum chromogranin A levels for testing.

Side effects and when to seek care immediately

Serious side effects

Hives, severe allergic reactions (such as hypotension, shortness of breath, facial swelling, etc.), fulminant hepatitis, liver dysfunction, jaundice, difficulty breathing, asthma attacks, breathing difficulties accompanied by pulmonary findings, interstitial pneumonia, adverse reactions on skin and mucous membranes (such as toxic epidermal necrolysis (Lyell syndrome), mucocutaneous syndrome (Stevens-Johnson syndrome), erythema multiforme), acute interstitial nephritis, serious neurological symptoms (such as seizures, coma, disorientation, confusion, etc.)

Mild side effects

Occasionally, rash, itching, blood disorders (such as erythrocytopenia, leukopenia, leukocytosis, eosinophilia, neutrophilia, lymphocytopenia, anemia, etc.), increases in ALT, AST, ALP, γ-GTP, LDH, total bilirubin, hypertension, myocardial infarction, ECG abnormalities, migraine, syncope, angina, degree block, palpitations, bradycardia, tachycardia, pulmonary embolism, ventricular tachycardia, thrombophlebitis, vasodilation, QTc prolongation, and heart.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture ingress, at room temperature between 1 to 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and prevent degradation.

Appearance and packaging

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/AluAlu packaging x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.