Medication info
Hyco Tablet 20mg (Simvastatin)

Hyco Tablet 20mg (Simvastatin)

Prescription medicationTablet경구
Ingredient · strength
Simvastatin›20mg / 1 tablet
Manufacturer / importer
(주)휴비스트제약
Appearance
Brownish-yellow oval film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201405436 · Approved 2014.11.21 · Insurance code 628800460

Summary

Main use
Reduction of cardiovascular disease risk and improvement of hyperlipidemia
Who takes it
Adults · Children
Adult dose
1. For reduction of the risk of cardiovascular disease: 40 mg once daily of Simvastatin. 2. For treatment of hyperlipidemia: - Standard initial dosing: 20 mg taken once daily in the evening. - Patients with mild to moderate hypercholesterolemia may start at 10 mg. - 5-40 mg once daily in the evening, with dosage adjusted according to LDL cholesterol levels, therapeutic goals, and patient response.
Child dose
For pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia: - Recommended initial dose: 10 mg once daily in the evening - Recommended dosage range: 10-40 mg once daily - Recommended maximum dose:

Ingredients

Manufacturer
(주)휴비스트제약

Efficacy & effects

Reduction of cardiovascular disease risk and improvement of hyperlipidemia

  • Coronary heart disease
  • diabetes
  • peripheral vascular disease
  • stroke
  • other cerebrovascular diseases
  • hypercholesterolemia
  • dyslipidemia
  • hypertriglyceridemia
  • heterozygous familial hypercholesterolemia
View approved original text

This medication helps reduce the risk of cardiovascular disease. It particularly lowers the risk of heart attacks or strokes in adult patients with a history of coronary heart disease, diabetes, peripheral vascular disease, and stroke, also reducing coronary mortality rates. Additionally, it is effective in treating hyperlipidemia, reducing cholesterol and triglycerides in various types of hypercholesterolemia and mixed dyslipidemia patients, while increasing good cholesterol (HDL). It is also used in conjunction with diet for pediatric patients with heterozygous familial hypercholesterolemia who have a family history. Overall, this medication improves cardiovascular health and decreases the risk of vascular-related diseases.

How to take

Adult dose

1. For reduction of the risk of cardiovascular disease: 40 mg once daily of Simvastatin. 2. For treatment of hyperlipidemia: - Standard initial dosing: 20 mg taken once daily in the evening. - Patients with mild to moderate hypercholesterolemia may start at 10 mg. - 5-40 mg once daily in the evening, with dosage adjusted according to LDL cholesterol levels, therapeutic goals, and patient response.

Child dose

For pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia: - Recommended initial dose: 10 mg once daily in the evening - Recommended dosage range: 10-40 mg once daily - Recommended maximum dose:

Precautions

This medication may cause muscle problems; therefore, if you experience muscle pain or weakness while taking it, consult your doctor immediately. There may be cases where this medication cannot be taken, so please inform your doctor if you have any allergies, severe liver disease, are pregnant or nursing, or are taking other specific medications. Those with poor liver function or high alcohol intake, decreased kidney function, or hypothyroidism should use this medication with caution. Elderly patients and women are at an increased risk of muscle disorders, so special care is required when taking this medication. This medication can affect liver function, so regular liver function tests should be performed, and if symptoms of hepatitis or jaundice occur, it should be stopped immediately. There are many drug interactions, so you must inform your healthcare provider about taking this medication when starting any new medications, especially not to be taken with strong specific antifungal agents, antibiotics, and immunosuppressants. Avoid grapefruit juice or large amounts of grapefruit as it may increase the risk of side effects from this medication. Pregnant women or those who may become pregnant should avoid taking this medication, and if pregnancy is confirmed during use, it should be stopped immediately. Nursing mothers should also discontinue breastfeeding while taking this medication, and it should not be used in children and patients under 10 years old. Increased blood sugar levels during treatment may increase the risk of diabetes, so those requiring blood sugar management should check their blood sugar levels regularly. In case of overdose, seek medical attention immediately for appropriate treatment. This medication should be kept out of reach of children and stored in its original container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, syncope

Mild side effects

  • Muscle pain
  • dyspepsia
  • headache
  • constipation
  • diarrhea
  • bloating
  • nausea
  • weakness
  • upper respiratory infection
  • atrial fibrillation
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  • gastritis
  • diabetes
  • insomnia
  • dizziness
  • bronchitis
  • sinusitis
  • eczema
  • urinary tract infection
  • alopecia
  • itching
  • gynecomastia
  • decreased libido
  • sexual dysfunction
  • cataract progression
  • ocular muscle paralysis
  • anemia
  • thyroid dysfunction
  • sensory disturbances
  • peripheral neuropathy
  • psychological disorders
  • anxiety
  • sleep disorders
  • depression
  • liver function test abnormalities
  • thrombocytopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container at a temperature between 1°C and 30°C at room temperature. This will help to maintain the medication's effectiveness.

Appearance and packaging

Appearance

Brownish-yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.