Omeprazole Capsule (Omeprazole)

Adult dose

I) Adults 1) Gastric ulcers: Administer omeprazole 20mg orally once daily. Most ulcers may heal within 4 weeks, although healing time may occasionally vary among patients. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other products, administering 40mg once daily usually results in healing within 8 weeks, although healing time may occasionally vary among patients. Repeat treatment if ulcers recur. 2) Short-term treatment of duodenal ulcers: Administer 20mg orally once daily. Most ulcers may heal within 2 weeks, although healing time may occasionally vary among patients. If healing is incomplete after the initial 2 weeks of treatment, continue treatment for an additional 2 weeks. In patients who have not responded to other products, administering 40mg once daily usually results in healing within 4 weeks, although healing time may occasionally vary among patients. Repeat treatment if ulcers recur. 3) Reflux esophagitis: Administer 20mg orally once daily. Most cases may heal within 4 weeks, although healing time may occasionally vary among patients. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. In patients who have not responded to other products, administering 40mg once daily usually results in healing within 8 weeks, although healing time may occasionally vary among patients. Repeat treatment if symptoms recur. 4) Zollinger-Ellison syndrome: The initial dose is 60mg orally once daily. Continue treatment, adjusting the dose appropriately for each patient. More than 90% of patients can be treated effectively with doses of 20 - 120mg per day. If administering more than 80mg per day, divide the dose into 2 doses per day. 5) Maintenance therapy for severe reflux esophagitis and peptic ulcers that are difficult to treat: Administer 20mg orally once daily. If symptoms recur, the dose may be increased to 40mg once daily. 6) Concomitant antibiotic therapy to prevent recurrence of duodenal ulcers infected with Helicobacter pylori: - Dual therapy: Administer this drug 20mg with amoxicillin 750 - 1000mg twice daily for 2 weeks. - Triple therapy: Administer this drug 40mg once daily or 20mg twice daily in combination with the following antibiotics. ① Administer clarithromycin 250mg and metronidazole 400mg twice daily for 1 week, or ② Administer amoxicillin 1g and clarithromycin 500mg twice daily for 1 week. If the treatment effect is insufficient, omeprazole monotherapy may be continued. 7) Treatment of symptoms of gastroesophageal reflux disease (GERD) (heartburn, regurgitation, etc.): Administer 20mg orally once daily. Healing is generally possible after taking it for 2-4 weeks. 8) Treatment of gastric or duodenal ulcers or erosions caused by nonsteroidal anti-inflammatory drugs (NSAIDs): Administer 20mg orally once daily. Most cases may heal within 4 weeks, although healing time may occasionally vary among patients. If healing is incomplete after the initial 4 weeks of treatment, continue treatment for an additional 4 weeks. 9) Maintenance prevention of gastric or duodenal ulcers or erosions and dyspeptic symptoms caused by NSAID use in patients with a history of gastric or duodenal lesions who are receiving long-term NSAID treatment: Administer 20mg orally once daily. * Swallow this drug whole with at least half a cup of water. Adjust the dose appropriately according to age and symptoms.

This drug should not be used in patients with an allergic reaction to its components. Caution should be taken when administering to patients with gastric ulcers suspected of malignancy, as symptom relief may delay cancer diagnosis. This drug cannot be used with certain antiviral or antiretroviral drugs, so consultation with a healthcare professional is necessary. Patients with genetic disorders that inhibit lactose breakdown should not take this drug. Patients with impaired liver function may have slower drug decomposition rates, so dosage should be adjusted, and especially in severe liver dysfunction, the maximum daily dosage should not be exceeded. Elderly patients may be more sensitive to the drug's effects and side effects, necessitating cautious use. Neurological side effects such as headache, dizziness, and drowsiness may occur frequently, and rarely serious symptoms such as confusion or hallucinations may develop. Liver function abnormalities may occur, so if liver enzyme levels rise, the drug should be discontinued, and there is a risk of encephalopathy in patients with severe liver disease. Kidney function may be affected; caution is particularly needed in patients with kidney disease. Gastrointestinal side effects such as diarrhea, abdominal pain, and nausea may occur frequently. Allergic reactions such as skin rash or itching may appear; if severe skin conditions arise, immediate discontinuation of the drug is necessary. Anaphylactic reactions such as angioedema or anaphylaxis have rarely been reported, so any unusual symptoms should be reported to a healthcare professional immediately. Cardiovascular symptoms such as chest pain or pulse irregularities may appear. There may be rare side effects such as a decrease in blood cell counts. Musculoskeletal symptoms such as myalgia or arthralgia may occur. Long-term use may lead to electrolyte abnormalities such as hypomagnesemia, requiring regular testing. This drug can increase bacterial growth in the stomach by suppressing gastric acid secretion, which may elevate infection risks. Long-term use may lead to vitamin B12 absorption impairment, so caution is advised. Autoimmune reactions similar to lupus may appear on the skin or systemically; if symptoms arise, immediate consultation with a healthcare professional is necessary. This drug may interact with various other medications, so patients should inform their healthcare provider if they are taking other drugs. Pregnant women or those who may become pregnant should consult a physician before taking this drug, and it is advisable to avoid use during breastfeeding. Safety in children has not been established, so careful use is required. Overdose may manifest as vomiting, diarrhea, headache, but most symptoms are temporary. This drug should be kept out of reach of children and stored in its original container without transferring to another container.

Headache, drowsiness, dizziness, insomnia, paresthesia, feeling faint, vertigo, confusion, agitation, aggression, hallucinations, depression, elevated liver enzymes, jaundice, hepatitis, liver failure, encephalopathy, interstitial nephritis, diarrhea, blackening of stools, constipation, nausea, vomiting, abdominal pain, abdominal bloating, dry mouth, stomatitis, gastrointestinal candidiasis, erythema, rash, blisters, urticaria, itching, dermatitis, bullous rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, photosensitivity, alopecia, angioedema, fever, bronchospasm, interstitial nephritis, anaphylactic shock, chest pain, tachycardia, bradycardia, palpitations, leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, back pain, arthralgia, muscle weakness, myalgia, gynecomastia, cough, asthenia, malaise, peripheral edema, increased sweating, blurred vision, visual impairment, taste disturbance, breast pain, breast lump, hyponatremia, erectile dysfunction, Clostridium difficile-associated diarrhea, hypomagnesemia, acute generalized exanthematous pustulosis, eosinophilia accompanied by systemic symptoms due to drug reaction, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyps, hypocalcemia, hypokalemia, Stevens-Johnson syndrome, toxic epidermal necrosis, eosinophilia accompanied by systemic symptoms due to drug reaction, acute generalized exanthematous pustulosis, acute interstitial nephritis, nausea, apathy

This drug should be stored in a tightly closed container to prevent air or moisture exposure. It is best to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

A hard capsule with a reddish-brown upper part and a pink lower part filled with light yellow enteric-coated granules.

Package unit

28 capsules/bottle