Desmopressin Acetate 0.1 mg

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, increase the dose at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical benefit within 4 weeks after the dose has been established.

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased up to 0.4mg. Whether to continue treatment should be determined after 3 months of administration, following discontinuation for at least 1 week.

This medication may affect the body's water and electrolyte balance, therefore, there is a risk of severe coma from hyponatremia and water intoxication, especially in elderly individuals and patients with certain diseases. Therefore, care should be taken to drink only enough water to quench thirst while taking this medication. Additionally, patients who have allergies to this medication or have habitual increases in urinary volume, heart failure, renal impairment, syndrome of inappropriate antidiuretic hormone secretion, hyponatremia, etc., should not use this medication. It is recommended for use only in enuresis patients with normal blood pressure. Patients with hypertension, cardiovascular disease, chronic kidney disease, women who are pregnant or may become pregnant, children, and elderly patients, as well as those at risk of water and electrolyte imbalance, should use this medication with caution, and it is important to treat any related diseases beforehand. This medication can cause side effects such as headache, nausea, skin allergic reactions, hyponatremia, weight gain, coma, and seizures; therefore, if symptoms occur, immediate consultation with medical personnel is required. During treatment, water intake must be strictly limited, especially controlling water consumption from 1 hour before to 8-12 hours after administration. Failure to restrict water intake can lead to serious side effects. This medication may interact with other drugs; therefore, caution is needed when taken with antidepressants, diuretics, corticosteroids, anticonvulsants, and non-steroidal anti-inflammatory analgesics. Before taking the medication, it is essential to inform healthcare providers of all medications being taken. Women who are pregnant or breastfeeding should carefully consider the impacts on the fetus or newborn when using this medication, and in cases of overdose, serious symptoms such as headache, nausea, and seizures may occur, requiring immediate emergency treatment.

• coma
• seizures
• weight gain
• hyponatremia
• emotional disturbances
• headache
• abdominal pain
• nausea
• allergic skin reactions
• dizziness

This medication is susceptible to air and moisture, so it must be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help maintain the medication's effectiveness and safety for a long time.

Appearance

White or pale yellow granules

Package unit

500 mg (pack)