Welluro Tablet 10mg (Solifenacin Succinate)

Adult dose

The usual adult dosage (including older adults) is 5mg once daily. If needed, the dosage may be increased to a maximum of 10mg once daily. This drug may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dosage adjustment is required in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dosage adjustment is required in patients with mild hepatic impairment. Use caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients taking potent cytochrome P450 3A4 (CYP3A4) inhibitors: Limit the maximum daily dose to 5mg in patients taking ketoconazole or other potent CYP3A4 inhibitors (e.g., ritonavir, nelfinavir, itraconazole).

This medication should not be used in patients with certain conditions. For example, patients with urinary retention symptoms, severe gastrointestinal problems, myasthenia gravis, glaucoma, allergy to this drug or its components, patients undergoing dialysis, or those with severe liver or kidney dysfunction should not take it. In addition, caution is advised for patients with difficulty in urine discharge, risk of gastrointestinal obstruction, severe renal or hepatic dysfunction, patients taking strong specific drugs together, those with esophageal disorders or autonomic nervous system problems. Common side effects of this medication include dry mouth, constipation, blurred vision, difficulty urinating, and dry eyes. Special care should be taken as serious gastrointestinal-related side effects may occur, especially with high doses. Rarely, serious allergic reactions such as angioedema or anaphylaxis can occur, and if such symptoms appear, the medication should be discontinued immediately and treatment sought. This medication requires caution as it may cause drowsiness or blurred vision when driving or operating machinery. Taking this medication with other anticholinergic drugs can increase its effectiveness or exacerbate side effects and may reduce the effectiveness of drugs that promote gastrointestinal motility. Since this medication is metabolized in the liver, taking it along with certain strong drugs may increase blood concentration, thus requiring dosage adjustment. Women who are pregnant or breastfeeding should use caution when taking this medication, and it is advisable to avoid its use during breastfeeding. The safety and efficacy of this medication in children have not been established, and it should not be administered to children. Overdose may result in headaches, dizziness, drowsiness, blurred vision, and appropriate treatment should be provided if necessary. Patients with heart disease or specific cardiac rhythm issues need to take special care when using this medication.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• nausea
• dyspepsia
• upper abdominal pain
• vomiting
• urinary tract infection

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to keep the storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

Bright pink round film-coated tablet

Package unit

100 tablets/box [10 tablets/PTP x 10], 30 tablets/bottle, 100 tablets/bottle