Rostojeng 10 mg (Rosuvastatin Calcium)

Adult dose

Administer the initial dose of 5 mg once daily at any time of the day regardless of meals. If a greater reduction in LDL cholesterol is needed, the maintenance dose may be adjusted to 10 mg once daily. The maintenance dose can be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum increase to 20 mg per day.

Child dose

The usual dosage range for pediatric patients aged 10 to 17 years is once daily between 5 mg and 20 mg. The dose should be adjusted according to individual treatment goals with intervals of 4 weeks or more.

This medicine should not be administered to certain patients. For instance, patients who are allergic to this medication, those with severely impaired liver function, patients with muscle diseases, those with certain renal impairments, as well as pregnant or nursing women should not use this drug. While using this medication, liver function and muscle health should be monitored periodically. Patients who consume a lot of alcohol or have a history of liver disease should be especially cautious and should inform their doctor immediately if they experience symptoms like muscle pain or weakness. This medication can affect muscles, potentially causing muscle pain or, rarely, muscle destruction, so use should be discontinued if severe muscle-related symptoms occur. Furthermore, this medication can interact with certain drugs; therefore, if taking other medications, patients must inform their healthcare provider. Special caution is needed when used with certain antibiotics, antifungals, immunosuppressants, etc. Women of childbearing potential should confirm that they are not pregnant and use appropriate contraception before taking this medicine. During pregnancy, this medication should not be taken, and it should be discontinued if pregnancy occurs. In case of overdose, there is no specific antidote, so treatment should be based on symptoms, and liver function and muscle enzyme levels should be monitored. Caution is also required when driving or operating machinery, as dizziness may occur. Finally, this medication contains lactose, so patients with lactose intolerance should be careful when taking it.

Serious side effects

Hypersensitivity reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscular weakness, rhabdomyolysis, immune-mediated necrotizing myopathy, acute renal failure, oliguria, chest tightness, difficulty breathing, severe headache, confusion, visual disturbances, paralysis, severe swelling accompanied by elevated blood pressure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• diarrhea
• fatigue

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius to effectively preserve the drug's efficacy and safety.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle