Omentin Tablet 625 mg (Amoxicillin Hydrate · Clavulanate Potassium)

Adult dose

For adults and children aged 12 years or older or weighing 40 kg or more, administer amoxicillin/clavulanate potassium at a dose of 250 mg/125 mg once every 8 hours orally, three times a day. In cases of severe or respiratory infections, the dose may be increased to 500 mg/125 mg once. In patients with renal impairment, the dosage should be adjusted according to creatinine clearance. For those with a creatinine clearance above 30 mL/min, no adjustment in dosage is necessary.

Child dose

For children under 12 years or those weighing less than 40 kg, dosing should be adjusted and administered in the same manner as in adults.

This medication is a beta-lactam antibiotic belonging to the penicillin group and may cause specific allergic reactions, so it should not be administered to patients with a history of hypersensitivity. Patients with viral diseases accompanied by infectious mononucleosis or lymphocytic leukemia may have an increased risk of rash, necessitating caution. Patients with a history of liver dysfunction or jaundice should use this medication cautiously, as hepatic damage may recur when taking it. Patients with liver impairment need to be cautious, as the medication may worsen liver function, and those with moderate to severe kidney impairment may require adjusted dosing due to increased drug concentration. Patients with an allergic constitution, the elderly, those in poor overall health, or those who have difficulty taking orally may have an increased risk of bleeding due to vitamin K deficiency and should be cautious. Patients with gastrointestinal disorders may have impaired drug absorption, so their condition should be checked carefully before administering. This medication may cause gastrointestinal side effects such as diarrhea, vomiting, and abdominal pain, and it is recommended to take it with meals to reduce gastrointestinal adverse reactions. Hepatic dysfunction may occur rarely, especially in the elderly or with long-term use, necessitating regular liver function tests. Severe skin reactions such as rash, urticaria, and in severe cases, Stevens-Johnson syndrome may occur due to hypersensitivity; if symptoms occur, administration must be stopped immediately, and medical advice should be sought. Hematological abnormalities such as leukopenia and thrombocytopenia are rarely reported, so regular blood tests are necessary. Central nervous system symptoms such as anxiety, confusion, and seizures may occur rarely, so any neurological symptoms should be reported immediately. Patients with renal dysfunction are at risk for kidney damage, so their kidney function should be monitored. Antibiotic use may disrupt the balance of intestinal bacteria, leading to dysbiosis such as candidiasis; thus, patients should consult a doctor if symptoms arise. Bleeding tendencies due to vitamin K deficiency may manifest; if bleeding symptoms occur, patients should inform their healthcare provider promptly. The medication should not be administered during the first trimester of pregnancy, and pregnant or nursing women should consult with their doctor before use. In children under 12 years of age or weighing less than 40 kg, there is limited experience, and its use is not recommended. Elderly patients may exhibit more adverse reactions due to diminished physiological functions; therefore, dosage and intervals should be adjusted and carefully monitored. This medication may interact with other drugs, so it is essential to consult a doctor or pharmacist before combining it with anticoagulants, gout medications, antibiotics, etc. In the event of overdose, symptoms such as vomiting, diarrhea, rash, and seizures may occur; administration must be stopped immediately, and appropriate treatment should be provided. Store in a special package to prevent moisture, and maintain a cool temperature between 1 and 25 degrees Celsius during storage. Following these storage instructions helps maintain the drug's effectiveness and safety.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, severe mucosal skin reactions (Stevens-Johnson syndrome), shock, severe rash, blisters, skin peeling, mucosal pain in mouth/eyes, dyspnea, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, hepatitis, cholestatic jaundice, sudden and severe reactions

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• nausea
• vomiting
• loss of appetite
• abdominal pain

This medication is stored in a special package to prevent moisture, and it must be kept at a cool temperature between 1 and 25 degrees Celsius. Proper storage preserves the drug's effectiveness and ensures safe use.

Appearance

White or nearly white rectangular film-coated tablets

Package unit

40 tablets (10 tablets/PTP x 4)