Acetodol Semi Tablets

Adult dose

For children aged 12 and older and adults: The dosage should be adjusted based on the patient's level of pain and treatment response. It is recommended to start with a dose of 4 tablets, with subsequent dosing intervals of at least 6 hours, ensuring that the total daily dose does not exceed 16 tablets. The effective minimum dose should be administered for the shortest possible duration. Avoid using this medication for longer than necessary, and if prolonged use is needed due to the nature and severity of the disease, ensure regular monitoring to confirm whether the medication should continue to be used. Elderly Administer the usual adult dose. However, for elderly patients over 75 years old, oral administration of Tramadol results in a 17% increase in elimination half-life, so dose administration should be spaced at least 6 hours apart. Renal impairment In moderate renal impairment patients (creatinine clearance of 10-30 ml/min), extend the dosing intervals to 12 hours. This medication is not recommended for severe renal impairment patients (creatinine clearance of less than 10 ml/min). Tramadol is eliminated very slowly during hemodialysis and filtration, so there is no need to re-administer this medication after dialysis to maintain analgesic effects. Hepatic impairment Careful consideration should be given to extending dosing intervals for patients with moderate hepatic impairment. This medication should not be administered to patients with severe hepatic impairment.

Child dose

For children aged 12 and older and adults: The dosage should be adjusted based on the patient's level of pain and treatment response. It is recommended to start with a dose of 4 tablets, with subsequent dosing intervals of at least 6 hours, not to exceed 16 tablets in one day.

This medication may put stress on the liver, so those who regularly consume more than three glasses of alcohol per day should consult a doctor or pharmacist before use. If a rash or allergic reaction occurs during treatment, discontinue use immediately and seek professional medical attention. Due to the risk of seizures, patients with a history of seizures or at high risk of seizures should use this medication cautiously, and should be especially careful when taking it with other specific medications. Severe allergic reactions may occur infrequently while using this medication; therefore, if symptoms such as difficulty breathing or hives arise, visit a medical facility immediately. Patients with acute and severe bronchial asthma should use this medication only in the presence of medical personnel, as it may cause difficulty in breathing. Taking this medication with central nervous system depressants or alcohol can result in severe drowsiness, respiratory depression, and coma, so avoid combined use or follow the guidance of a professional. Patients with head injuries or brain disorders should be cautious while taking this medication due to risks related to increased intracranial pressure. This medication can lead to both physical and psychological dependence, so it should be taken under professional supervision for long durations. Patients with impaired liver function should consult a doctor before taking this medication, and should be careful not to take other acetaminophen products simultaneously. Patients with specific genotypes may metabolize the active ingredient of this medication more quickly, which could increase the risk of respiratory depression; dose adjustment and close monitoring are required in such cases. Children under 12 years old or adolescents under 18 years old after certain surgeries should not be administered this medication, and adolescents aged 12 to 18 should avoid using it if there are risk factors. This medication can cause sleep apnea and hypoxemia; if these symptoms arise or worsen, consult medical staff immediately. Elderly patients or those at risk of hyponatremia should periodically check for the occurrence of hyponatremia while taking this medication. This medication is not to be administered to patients with allergies to specific ingredients, central nervous system drug addiction, severe respiratory depression, or severe liver and kidney diseases. While taking this medication, do not exceed the recommended dose, avoid combining it with other similar medications, and any sudden discontinuation may cause withdrawal symptoms; therefore, it should be tapered off gradually with consultation from a professional. This medication may cause drowsiness or decreased concentration while driving or operating machinery; therefore, caution is advised. In case of overdose, serious respiratory depression, seizures, liver damage, etc., may occur, requiring immediate emergency treatment, and in necessary cases, antidotes should be administered. This medication must be kept in a safe place out of the reach of children to prevent misuse and abuse by others.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound lethargy, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary changes

Mild side effects

• Loss of appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air from entering, and it is recommended to store it at room temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Pale yellow rectangular film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle