Cereon Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be administered with or without food. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, consider another treatment. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day if needed. Starting on the second day, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), reduce the dose to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if consumed by individuals who drink large amounts of alcohol daily, as it may increase the risk of gastrointestinal bleeding. It may increase the risk of cardiovascular diseases, so it should only be used at the lowest effective dose for the shortest duration, and medical consultation is necessary if cardiovascular symptoms occur. Serious gastrointestinal side effects such as perforation, ulcers, and bleeding may occur, so special caution is required for individuals with a history of gastrointestinal disorders or the elderly. This medication may cause allergic reactions, so patients with hypersensitivity or specific allergy histories should not take it. Patients with severely impaired liver or kidney function, active peptic ulcers, heart failure, pregnant or nursing women should not use this medication. Patients with a history of liver, kidney, or heart diseases should take it cautiously and monitor their conditions with regular tests. Possible adverse reactions while taking this medication include indigestion, headache, dizziness, skin rash, hypertension, edema, which require medical consultation if severe or persistent. Since the drug is metabolized in the liver, there may be interactions with certain medications; therefore, consult a specialist if taking other medications. Pregnant women or those planning to become pregnant should avoid taking this medication, and nursing mothers should consult with healthcare professionals before taking it. Elderly individuals require caution due to potential declines in kidney, liver, and heart function, and dosage adjustment may be necessary. Dizziness or drowsiness may occur while taking this medication, so it is advisable to avoid driving or operating machinery. Regular blood tests and liver and kidney function tests are necessary during long-term use, and the medication should be discontinued immediately if any abnormal findings occur. In case of overdose, symptoms such as vomiting, drowsiness, and nausea may appear, requiring immediate medical attention for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to other containers for safety.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, sensory deficit, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, generalized edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reaction, angioedema, loss of appetite, increased appetite, depression, nervous hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory infection, bronchial spasms, exacerbation of bronchial spasms, dyspnea, laryngitis, pneumonia, nosebleed, vocal cord disorder, vesicular dermatitis, dermatitis, nail disease, photosensitivity reaction, pruritus, erythematous rash, maculopapular rash, skin disease, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash accompanied by eosinophilia and systemic symptoms, arrhythmia, ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, sinus bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, solitary, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthritis, skeletal dysplasia, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, polyarthritis, contact dermatitis, injection site reaction, skin nodules, taste distortion, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, interstitial pneumonia, hepatitis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized pustular rash, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microangiopathic glomerulonephritis, menstrual disorders, chest pain

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is advisable to maintain the storage temperature between 15 and 30 degrees Celsius. Proper storage will help retain the medication's effectiveness and safety for a long time.

Appearance

A white capsule with yellow stripes filled with a white to pale yellow powder

Package unit

100 capsules/bottle, 30 capsules/bottle