Carvedilol Sustained Release Capsule 64 mg (Carvedilol)

Adult dose

Administer this medicine orally with food. Do not increase the dose or discontinue treatment without a physician's instructions. Because this medicine is an extended-release formulation, do not break, crush, or chew it; swallow the capsule whole. For reference, the daily doses of this medicine (extended-release formulation) corresponding to those of conventional carvedilol formulations are as follows: Daily dose of conventional formulation: 3.125 mg twice daily / Daily dose of extended-release formulation: 8 mg once daily Daily dose of conventional formulation: 6.25 mg twice daily / Daily dose of extended-release formulation: 16 mg once daily Daily dose of conventional formulation: 12.5 mg twice daily / Daily dose of extended-release formulation: 32 mg once daily Daily dose of conventional formulation: 25 mg twice daily / Daily dose of extended-release formulation: 64 mg once daily Daily dose of conventional formulation: 50 mg twice daily / Daily dose of extended-release formulation: 128 mg once daily Essential hypertension - Adults: Administer 16 mg once daily for 2 days, then increase to 32mg once daily. Usually, after administering 32 mg once daily for 2 weeks, if the effect is insufficient, the dose may be increased to 64mg once daily. The maximum daily dose of this medicine is 64mg. Essential hypertension - Elderly patients: Administration of 16 mg of this medicine once daily may provide a sufficient therapeutic effect. If the effect is insufficient after 2 weeks of treatment, the dose may be increased. Administer cautiously while monitoring the patient's condition. Chronic stable angina: For the first 2 days, administer 32 mg of carvedilol once daily, followed by 64 mg once daily. Chronic stable angina: Usually, administer 64 mg once daily for 2 weeks. If an increase is needed (excluding elderly patients), administer 128 mg once daily. Congestive heart failure: For initial treatment, generally administer 8 mg of carvedilol once daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 16 mg once daily for 2 weeks, then to 32 mg once daily for 2 weeks, and then to 64 mg once daily. Congestive heart failure: After taking each dose for at least 2 weeks, gradually increase the dose to the maximum dose tolerated by the patient. Congestive heart failure: The minimum effective dose of this medicine is 16 mg once daily. The maximum dose is 64 mg once daily for patients weighing 85 kg or less, and 128 mg once daily for patients weighing 85 kg or more.

This medication should not be used in certain patients. For example, it is contraindicated in cases of allergy to this medication or its components, severely impaired cardiac function, very slow heart rate, pulmonary diseases, metabolic abnormalities due to diabetes, pregnant or breastfeeding women, and so on. Special caution should be exercised when using this medication in diabetic patients, individuals with a history of allergies, and patients with heart disease. Additionally, elderly patients and those with reduced kidney or liver function, low blood pressure, or those taking certain medications should also be administered cautiously. This medication may cause central nervous system symptoms such as dizziness, headache, and fatigue, and it may slow down heart rate or lower blood pressure. Symptoms of heart failure may worsen, or swelling may develop, so regular checks of heart function are necessary. Various side effects, such as liver dysfunction, skin rashes, and blood disorders, may occur, so immediate consultation with a doctor is necessary if abnormal symptoms appear. When taking this medication for a long time, regular monitoring of heart function, blood pressure, ECG, etc. is essential, and sudden cessation can worsen heart symptoms, so it should be tapered off according to a physician's instructions. This medication may interact with several other drugs; therefore, if other medications are being taken, it is important to inform the doctor or pharmacist. Women who are pregnant or breastfeeding should not take this medication, and the safety for children or adolescents under the age of 18 has not been established. Elderly patients may experience increased drug concentration due to reduced liver function, so it should be started at a low dose and administered carefully. In case of overdose, severe symptoms such as low blood pressure, decreased heart rate, and difficulty breathing may occur, so immediate medical assistance should be sought, and since this medication is not removed by hemodialysis, specialized treatment is required. This medication should be stored in a lightproof container to avoid light exposure and kept out of reach of children, while transferring to other containers should be avoided.

• Dizziness
• headache
• fatigue
• weakness
• hallucination
• confusion
• depression
• sleep disturbances
• nightmares
• psychosis

This medication may be sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it is important to maintain a temperature of 1 to 30 degrees Celsius while storing the medication. Doing so helps to preserve the medication's efficacy over time.

Appearance

A hard capsule with a soft yellow color that contains immediate-release and sustained-release granules, ranging from white to light yellow.

Package unit

30 capsules/bottle