Epeman Tablet (Eperisone Hydrochloride)

Adult dose

Administer 50 mg of eperisone hydrochloride orally three times a day after meals. Adjust dosage based on age and symptoms.

This medication should not be used in certain patients. First, it should not be administered to patients who have had an allergic reaction to this medication. Second, it should not be used in patients with myasthenia gravis. Third, this medication contains lactose, so patients with genetic conditions such as lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medication. Additionally, caution should be exercised when administering this medication to the following patients. Patients with a history of hypersensitivity to drugs and patients with liver dysfunction should be closely monitored while using this medication as liver function may deteriorate. This medication can cause various side effects, so symptoms should be closely monitored during use. Rarely, shock reactions may occur; if symptoms appear, administration should be immediately stopped and appropriate treatment should be received. Liver dysfunction may occur, so liver function tests should be performed, and if abnormalities are found, administration should be halted. It may also affect kidney function, so kidney-related tests should be conducted to monitor condition. Blood abnormalities such as anemia may also rarely occur, so caution is advised. Additionally, hypersensitivity symptoms such as rash or itching, insomnia, drowsiness, headache, and paresthesia have been reported. Gastrointestinal symptoms may include nausea, vomiting, loss of appetite, constipation, and diarrhea. Urinary symptoms may include urinary disturbances, which should also be monitored for. During treatment with this medication, patients may experience systemic symptoms such as weakness, dizziness, and general malaise; thus, their condition should be closely monitored. Occasionally, facial flushing or sweating and swelling may also occur. In severe cases, immune system adverse reactions such as anaphylaxis, angioedema, and serious skin changes such as toxic epidermal necrolysis syndrome (Stevens-Johnson syndrome) may occur; therefore, if any symptoms such as fever, erythema, blisters, itching, eye congestion, or stomatitis occur, the medication should be immediately stopped and the patient should seek medical attention. Patients taking this medication may experience drowsiness, decreased concentration, and reduced reflexes; hence, they should avoid driving or operating dangerous machinery. Should symptoms such as weakness or staggering occur, dosage reduction or cessation of use may be necessary. Furthermore, taking this medication with similar drugs or certain muscle relaxants may lead to side effects such as accommodation disorders, so caution is advised when using in combination. Women who are pregnant or may become pregnant should only use this medication when the benefits of treatment outweigh the risks, as its safety during pregnancy has not been established. Nursing mothers are advised to avoid this medication whenever possible, and if unavoidable, to discontinue breastfeeding. The safety for use in children has not been adequately established, so it should be used cautiously in pediatric patients. Older adults may have decreased physical function, so monitoring and adjustment of the medication dosage are necessary. Lastly, this medication should be stored out of reach of children, and transferring to other containers may cause deterioration in quality or accidents, so care should be taken.

Serious side effects

Shock (severe allergic reaction), anaphylaxis, angioedema, toxic epidermal necrolysis and mucous membrane-skin-eye syndrome (Stevens-Johnson syndrome), liver dysfunction (increased ALT, AST, ALP), kidney abnormalities (proteinuria, increased BUN), anemia

Mild side effects

• Rash
• itching
• insomnia
• drowsiness
• headache
• limb paralysis
• rigidity
• limb tremors
• nausea
• vomiting

This medication should be stored in a tightly sealed container to prevent air exposure, preferably at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent degradation.

Appearance

White round film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 500 tablets/bottle, For export - 10 tablets/PTP [100 tablets (10 tablets/PTP x 10)]