Humet Tablet

Adult dose

This medication is taken 1 to 2 times daily before meals or with meals. Usually, treatment is initiated with a low dose, and the dosage may be gradually increased based on blood sugar monitoring results. The initial dose is glimepiride/metformin hydrochloride 2mg/500mg, and there is experience of increasing up to a maximum of 8mg/2000mg. Single-agent glimepiride generally does not provide additional effects at doses above 4mg per day, but

This medication can cause severe lactic acidosis or hypoglycemia, so caution is necessary. Especially when kidney function declines rapidly, the drug may accumulate in the body and increase risk, so regular kidney function tests should be performed. If there are symptoms of dehydration, severe diarrhea, vomiting, or fever, the medication should be temporarily discontinued and a doctor should be consulted. Additionally, caution should be exercised when taking it with other medications that can affect kidney function. As there is a potential increased risk of cardiovascular disease, the cardiovascular condition should be closely monitored while taking this medication. This drug should not be administered to patients with insulin-dependent diabetes or acute metabolic acidosis, severe liver or kidney dysfunction, or to women who are pregnant or breastfeeding. Elderly patients, those with malnutrition, irregular eating habits, or excessive alcohol consumption are advised to manage their medication more carefully due to the higher risk of hypoglycemia. During initial use, gastrointestinal symptoms (diarrhea, nausea, abdominal pain, etc.) may occur, but these are mostly temporary and improve naturally. If symptoms are severe, dosage adjustment may be necessary after consulting a doctor. If allergic reactions, skin rashes, or symptoms of blood abnormalities occur, notify medical personnel immediately, and in severe cases, the medication should be discontinued. This medication can lower vitamin B12 levels, so regular blood tests are needed to monitor this. In the case of overdose, hypoglycemia or lactic acidosis may occur, so it is essential to adhere strictly to the prescribed dosage, and if abnormal symptoms occur, visit a medical facility promptly. Additionally, it is advisable to avoid alcohol consumption while taking this medication, and be cautious of symptoms of hypoglycemia or dizziness when driving or operating machinery. Lastly, children, the elderly, and women who are pregnant should always consult a doctor before taking this medication, and routine blood sugar and kidney function tests should be performed to ensure safe treatment.

Serious side effects

Hives, severe swelling (edema), difficulty breathing and respiratory distress, severe allergic reactions, severe skin reactions, liver abnormalities (jaundice), serious neurological symptoms (severe headache, confusion, seizures, paralysis, visual disturbances), decreased urine output and severe edema, lactic acidosis, hypoglycemia, thrombocytopenic purpura, severe hypoglycemia, severe allergic reactions (shock), heart attack, heart failure, cardiac arrest, ketoacidosis, acute

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain), taste disturbance, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, granulocytopenia, agranulocytosis, pancytopenia, decreased and deficiency of vitamin B12, peripheral neuropathy, increased liver enzymes, liver function impairment, hepatitis, allergic vasculitis, photosensitivity, decreased serum sodium concentration, hypothyroidism,

This medication may be sensitive to air and humidity, so it must be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness and safety of the medication over time.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle