Medication info
Kongbrukjeong 2.5 mg (Bisoprolol Fumarate)

Kongbrukjeong 2.5 mg (Bisoprolol Fumarate)

Prescription medicationTablet경구
Ingredient · strength
Bisoprolol Fumarate›2.5mg / 1 tablet
Manufacturer / importer
에리슨제약(주)
Appearance
White film-coated tablet, heart-shaped, convex on both sides with a score line on one side
Packaging
30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201404183 · Approved 2014.09.11 · Insurance code 620500110

Summary

Main use
Treatment of left ventricular systolic dysfunction (stable chronic heart failure)
Who takes it
Adults · Children
Adult dose
As Bisoprolol Fumarate, it is administered orally once daily. The initial dose is 1.25 mg once daily, and the dosage can be gradually increased to 2.5 mg, 3.75 mg, 5 mg, 7.5 mg, and 10 mg at intervals of more than 2 weeks while monitoring tolerance. The maintenance dose is 10 mg once daily. The recommended maximum dose is 10 mg once daily. During the dosage increase period, blood pressure, heart rate, and other patient conditions and heart failure symptoms should be closely monitored.
Child dose
Due to the lack of experience in pediatric use, administration is not recommended.

Ingredients

Manufacturer
에리슨제약(주)

Efficacy & effects

Treatment of left ventricular systolic dysfunction (stable chronic heart failure)

  • Reduced left ventricular systolic function
  • stable chronic heart failure
View approved original text

This medication is used for the treatment of stable chronic heart failure with reduced left ventricular systolic function. It is mainly administered in conjunction with ACE inhibitors and diuretics, and may also be combined with cardiac glycosides as needed to alleviate symptoms and improve heart function. This can enhance the quality of life for heart failure patients and prevent the worsening of symptoms.

How to take

Adult dose

As Bisoprolol Fumarate, it is administered orally once daily. The initial dose is 1.25 mg once daily, and the dosage can be gradually increased to 2.5 mg, 3.75 mg, 5 mg, 7.5 mg, and 10 mg at intervals of more than 2 weeks while monitoring tolerance. The maintenance dose is 10 mg once daily. The recommended maximum dose is 10 mg once daily. During the dosage increase period, blood pressure, heart rate, and other patient conditions and heart failure symptoms should be closely monitored.

Child dose

Due to the lack of experience in pediatric use, administration is not recommended.

Precautions

This medication lacks sufficient usage experience in patients with certain heart diseases or severely impaired kidney or liver function, and should be used with caution. Bronchodilators should be used in patients with bronchial asthma or chronic obstructive pulmonary disease, and caution is needed as asthma patients may experience increased airway resistance. This medication can worsen allergic reactions and may mask symptoms in patients with hyperthyroidism; caution is advised. Abrupt discontinuation can risk worsening heart conditions, so it should be tapered off gradually as directed by a physician. It should not be given to patients with diabetic ketoacidosis, severe bradycardia, cardiogenic shock, acute heart failure, and other specific conditions. Women who are pregnant or may become pregnant should avoid using this medication as it can be harmful to the fetus. If nursing, it is advisable to either avoid this medication due to its potential secretion in breast milk or stop breastfeeding. Safety in pediatric patients has not been confirmed, so its use is not recommended. In the elderly, it should be started at a low dose while closely monitoring their condition. This medication can interact with other drugs, so patients must inform their doctor of all medications they are taking, especially when using with calcium channel blockers, central nervous system drugs, insulin, etc. Caution is needed while driving or operating machinery due to individual variations, particularly early in treatment or during medication changes. Overdose can result in severe bradycardia, hypotension, and bronchospasm; immediate medical attention is needed.

Side effects and when to seek care immediately

Mild side effects

Bradycardia, worsening of heart failure, coldness or numbness in the limbs, hypotension, dizziness, headache, nausea, vomiting, diarrhea, constipation, weakness, fatigue, atrioventricular conduction disturbances, orthostatic hypotension, sleep disturbances, depression, bronchospasm, muscle atrophy and spasms, nightmares, hallucinations, decreased tear production, hearing impairment, allergic rhinitis, hypersensitivity (itching, redness, rash), hepatitis, sexual dysfunction, conjunctivitis, exacerbation of psoriasis or psoriasis-like rash, hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White film-coated tablet, heart-shaped, convex on both sides with a score line on one side

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.