Medication info

Actirison Tablets (Eperisone Hydrochloride)

Prescription medication경구Expired
Ingredient · strength
Eperisone Hydrochloride›50mg / 1 tablet
Manufacturer / importer
안국약품(주)
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Expired

MFDS item code 201404043 · Approved 2014.08.29

This product's status changed to Expired on 2024.08.29. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of musculoskeletal pain-related muscle spasms and neurological rigidity
Who takes it
Adults
Adult dose
As eperisone hydrochloride, the dosage is 50 mg orally three times a day after meals. The dosage may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
안국약품(주)

Efficacy & effects

Improvement of musculoskeletal pain-related muscle spasms and neurological rigidity

  • Painful muscle spasms associated with musculoskeletal diseases
  • cervical spondylosis
  • shoulder periarthritis
  • low back pain
  • spastic paralysis
  • cerebrovascular disorders
  • spastic spinal paralysis
  • cervical spondylosis
  • postoperative sequelae
  • post-traumatic sequelae
  • amyotrophic lateral sclerosis
  • cerebral palsy
View approved original text

This medication is primarily used for various symptoms associated with musculoskeletal and neurological conditions. It helps alleviate painful muscle spasms such as those found in cervical spondylosis, shoulder periarthritis, and low back pain related to musculoskeletal disorders. It is also effective for spastic paralysis due to neurological disorders, improving muscle rigidity caused by a variety of conditions including cerebrovascular disorders, spastic spinal paralysis, cervical spondylosis, as well as postoperative or post-traumatic sequelae. Additionally, it is used for various cerebrospinal diseases including amyotrophic lateral sclerosis, cerebral palsy, and spinocerebellar degeneration. This medication alleviates muscle rigidity and pain, thereby making the daily lives of patients more comfortable. Therefore, it is used to treat muscle rigidity and pain that occur in musculoskeletal and neurological diseases.

How to take

Adult dose

As eperisone hydrochloride, the dosage is 50 mg orally three times a day after meals. The dosage may be adjusted as appropriate according to age and symptoms.

Precautions

This medication should not be used in certain patients. First, persons allergic to this medication or those with myasthenia gravis should not take this medication. Additionally, this medication contains lactose, so individuals with genetic issues such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should also avoid it. This medication should be used with caution in patients with a history of drug allergies or impaired liver function. Patients with liver dysfunction should be particularly careful as it may worsen liver function. It is important to be mindful that various side effects can occur while taking this medication. Rarely, shock may occur, so if any unusual symptoms appear, the medication should be discontinued immediately, and treatment should be sought. Liver enzyme levels may rise, so regular monitoring of liver function tests is necessary, and rare kidney dysfunction may also need to be observed. Hyperreactivity such as anemia, skin rash, or itching can occur. Neurological symptoms may include insomnia, drowsiness, headache, and tingling in the hands and feet, while gastrointestinal symptoms can include nausea, vomiting, loss of appetite, constipation, diarrhea, and abdominal pain. Urinary issues may manifest as difficulty urinating or symptoms of incontinence. Other symptoms that may occur include weakness, dizziness, decreased muscle tone, facial flushing, sweating, and edema, so symptoms should be closely monitored. If severe skin reactions such as Stevens-Johnson syndrome occur, medications should be stopped immediately, and a healthcare professional should be consulted. During treatment with this medication, drowsiness or impaired concentration may occur, so it is advisable to avoid driving or operating dangerous machinery. Additionally, taking this medication with similar medications or certain muscle relaxants may result in side effects, so healthcare providers should be informed. Women who are pregnant or may become pregnant should take this medication cautiously due to the uncertainty about its safety, and breastfeeding mothers should either avoid taking it or stop breastfeeding if possible. The safety of this medication has not been adequately confirmed in children, so caution should be exercised when using it, and elderly patients may require special attention due to potentially decreased bodily function and dosage adjustments.

Side effects and when to seek care immediately

Serious side effects

Shock (severe allergic reaction), liver abnormalities (increased ALT, AST, ALP), kidney abnormalities (proteinuria, increased BUN), anemia, anaphylactic reaction (severe allergic reaction), angioedema (severe swelling), toxic epidermal necrolysis and mucous membrane-skin-eye syndrome (severe skin adverse reactions).

Mild side effects

  • Rash
  • itching
  • insomnia
  • drowsiness
  • headache
  • body stiffness
  • limb tremors
  • nausea
  • vomiting
  • loss of appetite
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  • gastrointestinal discomfort
  • thirst
  • constipation
  • diarrhea
  • abdominal pain
  • abdominal bloating
  • stomatitis
  • urinary retention
  • incontinence
  • feeling of residual urine
  • weakness
  • staggering
  • general malaise
  • dizziness
  • decreased muscle tone
  • facial flushing
  • sweating
  • drowsiness
  • decreased attention
  • decreased concentration
  • and decreased reflex activity.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and should be kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for longer.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.