Rosuvastatin Tablets 5 mg (Rosuvastatin Calcium)

Adult dose

For patients with primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia, administer once daily 5 mg as the initial dose at any time during the day, regardless of meals. If a greater reduction in LDL cholesterol is needed, the maintenance dose is adjusted to 10 mg once daily, which can be increased to a maximum of 20 mg per day at intervals of 4 weeks or more.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is administered once daily in the range of 5 mg to 20 mg, adjusting the dose according to individual patients at intervals of 4 weeks or more.

This medication should not be used in certain patients. For example, patients with allergies to its ingredients, severe liver problems, muscle diseases, or severely impaired kidney function may be at risk if they take this medication. Pregnant or breastfeeding women, as well as women of childbearing potential, should consult their doctor and use appropriate contraception. Additionally, patients at high risk for muscle disease should avoid high doses of this medication. As this medication contains lactose, patients with genetic issues such as lactose intolerance should not take it. This medication can affect liver function, so patients with a history of liver disease or excessive alcohol consumption should undergo regular liver function tests before and during treatment. If symptoms such as muscle pain or weakness occur, they should notify their doctor immediately and discontinue treatment if necessary. It is especially safe to stop this medication if muscle-related symptoms are severe or if blood tests show significantly elevated markers of muscle damage. This medication can interact with other drugs, so anyone taking other medications should inform their doctor or pharmacist. Caution is particularly advised when taken with certain antiviral drugs, immunosuppressants, antifungals, and antibiotics. Moreover, high-dose combinations with fibrate-class medications are prohibited. Pregnant or breastfeeding individuals should not take this medication as its safety has not been established, and women planning to become pregnant should use adequate contraceptive methods. There is no specific antidote for overdose, so treatment should be administered based on symptoms, monitoring liver function and muscle damage. This medication may cause dizziness, so caution is needed when driving or operating machinery. Finally, if severe skin reactions or serious liver damage symptoms occur while taking this medication, it should be stopped immediately, and medical advice should be sought.

Serious side effects

Allergic reactions including urticaria and angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, severe muscle weakness, ophthalmoplegia, thrombocytopenia, jaundice, hepatitis, increased transaminases, Stevens-Johnson syndrome, eosinophilia with systemic symptoms drug reaction (DRESS), immune-mediated necrotizing myopathy, acute kidney failure, oliguria, memory loss, peripheral neuropathy, polyneuropathy, dyspnea

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• chest discomfort
• diarrhea

This medication should be stored in a sealed container to prevent exposure to air or moisture, and it is best to keep it at room temperature between 1°C and 30°C. This helps to maintain the medication's effectiveness for a longer period.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2)