Lopatan Tablets 10 mg (Rosuvastatin Calcium)

Adult dose

Patients with primary hypercholesterolemia, mixed dyslipidemia, dysbetalipoproteinemia, and homozygous familial hypercholesterolemia can take this drug at any time during the day, regardless of meals. The initial dose is 5 mg once daily, and it may be adjusted to maintain a dose of up to 10 mg once daily as needed. The maintenance dose should be adjusted based on LDL cholesterol levels and patient response at intervals of 4 weeks or more, with a maximum of 20 mg per day.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is 5 mg to 20 mg once daily. The dose should be adjusted according to treatment goals at intervals of 4 weeks or more.

This drug should not be taken by certain patients. For example, it should not be administered to patients who are allergic to its components, patients with severe liver dysfunction, patients with muscle diseases, and patients with significantly impaired kidney function. Pregnant or breastfeeding women, as well as women of childbearing age who are not using adequate contraception, should also avoid taking this drug. It is important to monitor liver function tests and muscle conditions periodically while using this drug. Precautions should be taken, especially for patients with a history of liver disease or heavy alcohol consumption. If symptoms of myalgia, muscle weakness, or muscle damage occur, immediate medical attention should be sought. This drug may exacerbate muscle diseases, so discontinuation may be necessary if such symptoms occur. Additionally, interactions may arise when taken with other medications, so it is essential to inform healthcare providers of all medications being taken, particularly antivirals, immunosuppressants, antibiotics, and fibrates. This drug can elevate blood glucose levels, so patients at risk for diabetes should pay attention to blood glucose management. Pregnant and breastfeeding women should not take this drug, and women planning to become pregnant should use appropriate contraceptive methods. There is no specific antidote for overdose, so immediate medical care and assessment should be sought. This drug may cause symptoms like dizziness, so caution should be exercised when driving or operating machinery. Lastly, it is important to consult healthcare professionals immediately if any adverse reactions occur while taking this medication.

Serious side effects

Allergic reactions including urticaria, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, myopathy (including myositis), immune-mediated necrotizing myopathy, jaundice, hepatitis, severe muscle weakness, oculobulbar weakness, cough, dyspnea, acute renal failure, thrombocytopenia, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• myalgia
• weakness
• pruritus
• rash
• hematuria

This drug should be stored in a tightly closed container to protect it from air and moisture, and it is best kept at temperatures between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent deterioration.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle