Clariwon Tablet (Clarithromycin)

Adult dose

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment period is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. ○ Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used in certain patients. For example, it should not be administered to individuals who are allergic to any of the components in this medication or have a history of allergy to specific classes of antibiotics. Furthermore, it is safe to avoid this medication in patients who are taking drugs that may affect heart rhythm, in those with severely impaired liver or kidney function, and in pregnant or nursing women. Caution is especially needed in administering this medication to patients with poor liver or kidney function, those with heart disease, elderly patients, and those taking other antibiotics. This medication can cause a variety of side effects, including allergic reactions, gastrointestinal disturbances, skin rashes, liver function anomalies, kidney function impairment, central nervous system symptoms, etc., so if any unusual symptoms occur, it is essential to consult a doctor immediately. To prevent antibiotic resistance, use this medication only for the minimum necessary duration, and if symptoms worsen or new infection symptoms appear, discontinue use and consult healthcare professionals. This medication interacts with many other drugs, so it is essential to inform healthcare providers if you are taking other medications, especially when used in conjunction with heart-related medications, anticoagulants, certain antiviral drugs, and anticonvulsants. It is recommended that pregnant or nursing women avoid using this medication, and if necessary, they should consult with a professional fully before use. Dosage adjustments or caution are necessary for children and the elderly, especially if kidney or liver function is impaired. During the use of this medication, symptoms such as dizziness and confusion may occur, requiring caution when driving or operating machinery. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may occur, necessitating an immediate visit to a medical facility for appropriate treatment. Finally, this medication's absorption may be reduced when taken with specific foods or other medications, so it is crucial to follow the healthcare provider's guidelines regarding administration.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, hives, mild skin erythema, angioedema, joint swelling, drug rash, abdominal distention, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosa erosion, epigastric pain, polydipsia, transient tooth discoloration, pancreatitis, amylase increase, taste disturbance, loss of appetite, constipation, discoloration of feces, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, leukopenia, thrombocytopenia, pancytopenia, hemolytic anemia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremor, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, reversible hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hearing impairment, hypoglycemia, tinnitus, hearing loss, purpuric rash, acute generalized pustular psoriasis, vasodilation, bleeding, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, teeth discoloration, rash, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, mental changes in administration, obsessive behavior, hypokalemia, hypoxemia

This medication is sensitive to light and should be stored in a dark place, ideally at room temperature between 1 to 30 degrees Celsius. It should also be stored in a sealed container to prevent it from coming into contact with air.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle