Nexrazole 20mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquid, and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks If symptoms persist, an additional 4 weeks of treatment is required. - Maintenance therapy for preventing recurrence of esophagitis: 20 mg once daily - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily

Children's dosage

Adolescents aged 12 and older - Treatment of gastroesophageal reflux disease: 40 mg once daily for 4 weeks If symptoms persist, an additional 4 weeks of treatment is required. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis:

This medication should not be used in certain patients. Individuals who have allergies or have experienced hypersensitivity reactions to this medication, its ingredients, or benzimidazole derivatives should not take it. Additionally, individuals allergic to amoxicillin or clarithromycin should avoid this medication when combined with it for the eradication of Helicobacter pylori. It is also recommended not to use this medication in patients taking certain heart-related medications, nursing women, or those with a history of myocardial infarction. This medication contains dye number 4, so individuals with allergic reactions or hypersensitivity to this dye should use it with caution. During treatment, various adverse reactions can occur, including headache, abdominal pain, diarrhea, skin rash, muscle pain, and dizziness. Particularly rare events include blood abnormalities, severe allergic reactions, liver function abnormalities, and severe skin reactions, which require immediate consultation with healthcare professionals if symptoms appear. Since this medication suppresses gastric acid secretion, there may be a slight increase in the risk of bacterial infections in the stomach. Furthermore, long-term use may increase the risk of fractures, so periodic examinations are necessary for individuals at risk of osteoporosis. Long-term use of this medication can lead to hypomagnesemia, so regular blood tests are important, especially for those taking it for more than a year or taking medications that lower magnesium levels. This medication interacts with many other drugs, so it is necessary to consult a physician or pharmacist, especially if you are taking antibiotics, antiviral drugs, anticoagulants, or antiepileptic drugs. During pregnancy, data on the safety of this medication is limited, so it should be used cautiously if you are pregnant or planning to become pregnant. Nursing women are advised not to take this medication. In case of overdose, there is no specific antidote, so it is important to receive appropriate treatment according to the symptoms. This medication should be kept out of reach of children, and transferring it to another container is not advisable as it may affect quality.

Serious side effects

Urticaria, severe swelling, angioedema, anaphylaxis, shock, severe rash with high fever, blistering, skin peeling, mucous membrane pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, eosinophilia with systemic symptoms (DRESS syndrome), hepatitis, liver failure, jaundice, encephalopathy, rhabdomyolysis, myocardial infarction, severe edema,

Mild side effects

Headache, dizziness, paraesthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, hyperhidrosis, Clostridium difficile-associated diarrhea, abdominal distention, allergic reactions,

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. It is recommended to maintain a storage temperature between 1°C and 30°C.

Appearance

Pale pink, round film-coated tablet

Package unit

28 tablets (14 tablets/PTP*2)