Clarithromycin Tablet 250mg (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this drug twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, or rifampin. Helicobacter pylori eradication in patients with duodenal ulcers: Administer this drug 500mg (potency) three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults Children under 12 years of age: Use clarithromycin dry syrup.

This medication should not be used in patients with allergies to certain components or those with a history of hypersensitivity to similar antibiotics. Additionally, it is safe to avoid in patients taking medications that may affect heart rhythm or those with severe liver or kidney dysfunction. It is advisable not to use this medication in pregnant or breastfeeding women, and it should not be administered to patients with central nervous system infections. Caution should be exercised when administering to patients with impaired liver or kidney function, elderly patients with heart disease, and patients taking other antibiotics. Rarely, this medication may cause serious allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney issues, skin rashes, neurological abnormalities, etc., so any unusual symptoms should be reported to a healthcare professional immediately. Due to numerous drug interactions, it is essential to inform doctors or pharmacists about any other medications taken, especially when combining with heart-related drugs, anticoagulants, antidiabetic medications, and immunosuppressants. This medication should only be taken for the necessary duration to prevent the emergence of resistant bacteria, and caution is needed as prolonged or repeated use may result in dysbiosis. Pregnant women or nursing mothers should avoid this medication, and it is crucial to consult a specialist before administering it to children or the elderly. Overdose may lead to gastrointestinal disturbances or psychiatric symptoms, so the prescribed dosage must be adhered to, and immediate treatment should be sought if adverse reactions occur. Lastly, this medication should be stored away from direct sunlight and at room temperature, and refrigeration is not recommended.

Anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, membrane colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormality, eosinophilia, eosinophilic pulmonary infiltrate, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, delirium, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, total bilirubin increase, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, angular cheilitis, oral candidiasis, QT prolongation, ventricular tachycardia, ventricular fibrillation, malaise, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory impairment, hypoglycemia, tinnitus, hearing impairment, vomiting, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea, nephritis, phlebitis at the injection site, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, albumin-globulin ratio abnormalities, elevated serum alkaline phosphatase, increased serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, cardiac arrest, atrial fibrillation, premature contractions, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating

This medication must be stored in a tightly closed container to avoid exposure to air or moisture and should be kept at a temperature between 1°C and 30°C. Storing it in this manner will help maintain the medication's effectiveness over time.

Appearance

Yellow oval film-coated tablet with a vanilla flavor

Package unit

30 tablets/bottle, 100 tablets/bottle