Medication info
Candera Plus Tablets 16/12.5 mg (Candesartan Cilexetil, Hydrochlorothiazide)

Candera Plus Tablets 16/12.5 mg (Candesartan Cilexetil, Hydrochlorothiazide)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
하나제약(주)
Appearance
Light orange rectangular tablet with a score line on one side
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 201403533 · Approved 2014.07.31 · Insurance code 657805340

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dose for this medication is 1 tablet once daily, taken regardless of meals. For adults, the dosage of candesartan cilexetil can be adjusted before switching to this medication. No separate dosage adjustment is required for the elderly. For patients with reduced intravascular effective blood volume or renal impairment, dosage adjustment for candesartan cilexetil should be considered.

Ingredients

Manufacturer
하나제약(주)

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

Essential hypertension is treated using a combination therapy when individual components are insufficient for therapeutic effect, helping to stabilize blood pressure and reduce the occurrence of complications. This medication is effective in managing essential hypertension.

How to take

Adult dose

The recommended dose for this medication is 1 tablet once daily, taken regardless of meals. For adults, the dosage of candesartan cilexetil can be adjusted before switching to this medication. No separate dosage adjustment is required for the elderly. For patients with reduced intravascular effective blood volume or renal impairment, dosage adjustment for candesartan cilexetil should be considered.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Individuals with an allergy to any components of this medication or sulfonamide drugs, severe impairment of kidney or liver function, certain hematological disorders or electrolyte imbalances, pregnant or breastfeeding women should not take this medication. Those with too low blood pressure or unstable body fluid and electrolyte balance should use this medication with caution, and those with liver disease or heart valve disease should also use it carefully. This medication may affect the concentrations of potassium, sodium, calcium, etc., in the blood, so it is important to regularly check electrolyte status through blood tests. The hydrochlorothiazide component can make the skin sensitive to sunlight, increasing the risk of skin cancer, so sunlight exposure should be avoided, and skin condition should be monitored frequently. During the use of this medication, symptoms such as headache, dizziness, fatigue, indigestion, and cough may occur. If these symptoms worsen or persist, it is advisable to consult a physician. When taken with other blood pressure medications, diuretics, potassium supplements, or non-steroidal anti-inflammatory drugs (NSAIDs), the efficacy and side effects may change, so it is essential to inform healthcare professionals of any current medications. Elderly patients should be monitored more closely while taking this medication as there is a risk of too low blood pressure or kidney function deterioration. Pregnant women or those planning to become pregnant should not take this medication, and breastfeeding women should consult a professional before use as it may affect the infant. An overdose of this medication may result in symptoms such as low blood pressure, dizziness, and electrolyte imbalance, so if symptoms are suspected, immediate medical attention should be sought for appropriate treatment. Keep this medication out of the reach of children and store it in its original packaging to prevent misuse or quality degradation. Caution is needed when driving or operating machinery as dizziness or fatigue may occur, and these activities should be avoided during such times.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory anomalies accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances,

Mild side effects

  • Headache
  • back pain
  • dizziness
  • respiratory infections
  • symptoms similar to influenza
  • sinusitis
  • bronchitis
  • urinary tract infections
  • nausea
  • contusions
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  • tachycardia
  • fatigue
  • abdominal pain
  • pharyngitis
  • dyslipidemia
  • nasopharyngitis
  • cough
  • increased blood sugar
  • elevated serum uric acid
  • elevated ALT (SGPT)
  • decreased hemoglobin
  • elevated serum AST (SGOT)
  • increased creatinine
  • increased urea
  • increased potassium
  • decreased sodium
  • leukopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is best to store it at a cool temperature below 30°C. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

Light orange rectangular tablet with a score line on one side

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.