Medication info
Glypidin Tablets 2mg (Glimepiride)

Glypidin Tablets 2mg (Glimepiride)

Prescription medicationTablet경구
Ingredient · strength
Glimepiride›2mg / 1 tablet
Manufacturer / importer
(주)씨엠지제약
Appearance
Green rectangular tablet
Packaging
Bottle packaging: 30 tablets, 300 tablets
Approval status
Active

MFDS item code 201403458 · Approved 2014.07.29 · Insurance code 648602700

Summary

Main use
Improvement of blood sugar control in type 2 diabetes
Who takes it
Adults
Adult dose
Individual dose adjustment needs to be made for each patient. It should be taken whole, without chewing, with more than half a cup of water. This medication is taken orally once a day. It should be ingested before breakfast or just before the first meal. Start with a dosage of 1 mg daily, as Glimepiride, and increase the dose by 1 mg at 1-2 week intervals. Generally, doses above 4 mg do not provide additional benefit; however, some patients have shown better metabolic control with increments up to 6 mg (or

Ingredients

Manufacturer
(주)씨엠지제약

Efficacy & effects

Improvement of blood sugar control in type 2 diabetes

View approved original text

This medication is used to improve blood sugar control in patients with type 2 diabetes. It is effective when taken in conjunction with dietary therapy and exercise for those who find blood sugar control challenging. It can also be administered as a monotherapy, but may be combined with oral hypoglycemic agents or insulin as needed. It is helpful for blood sugar control when used alongside metformin in patients who have insufficient response to sulfonylureas or metformin as monotherapy. This medication plays an important role in managing type 2 diabetes and improves blood sugar control.

How to take

Adult dose

Individual dose adjustment needs to be made for each patient. It should be taken whole, without chewing, with more than half a cup of water. This medication is taken orally once a day. It should be ingested before breakfast or just before the first meal. Start with a dosage of 1 mg daily, as Glimepiride, and increase the dose by 1 mg at 1-2 week intervals. Generally, doses above 4 mg do not provide additional benefit; however, some patients have shown better metabolic control with increments up to 6 mg (or

Precautions

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or in a coma. Additionally, patients who have had an allergic reaction to this medication, its ingredients, or sulfonylureas should not be given this medication. There is no experience in using this medication in patients with severe liver or kidney dysfunction, and it is recommended to switch to insulin therapy for these patients. Women who are pregnant or may become pregnant, as well as nursing mothers, should also avoid taking this medication. For patients with severe infections, before and after surgery, or severe trauma, insulin therapy is more suitable than this medication. In cases of gastrointestinal disturbances such as diarrhea or vomiting, caution must be taken as improper food absorption may increase the risk of hypoglycemia. This medication contains lactose, so it should not be given to patients with lactose intolerance or certain genetic metabolic disorders. During the first week of administration, the risk of hypoglycemia is high, so blood sugar should be monitored very closely. Patients with poor nutritional status, irregular eating habits, skipping meals, excessive exercise, and imbalanced carbohydrate intake are also at increased risk for hypoglycemia. Patients consuming alcohol or with decreased kidney and liver function, as well as those who overdose on this medication, may also have an increased risk of hypoglycemia. Elderly patients or those with endocrine disorders, as well as those taking multiple medications, should also be careful. Use with caution in patients with an allergy to Yellow 4 (tartrazine) present in this medication. Symptoms of hypoglycemia can vary and may include headache, severe hunger, nausea, fatigue, anxiety, confusion, drowsiness, loss of consciousness, etc. In severe cases, this can lead to seizures or coma, so immediate action must be taken upon symptom onset. Various side effects such as blurred vision, gastrointestinal disturbances, liver dysfunction, hematologic abnormalities, and allergic reactions may occur, so report any unusual symptoms to a doctor or pharmacist. This medication is effective when taken with regular dosing, along with dietary therapy, exercise therapy, and weight management. In the event of hypoglycemia, be prepared to consume sugar-containing foods to raise blood sugar levels immediately. When receiving treatment at another hospital or pharmacy, be sure to inform them that you are currently taking this medication, and insulin therapy may need to be initiated during stressful situations or surgeries. This medication is excreted through the kidneys, so dosage adjustment is necessary in elderly patients or those with diminished kidney function. In the case of overdose, emergency measures like inducing vomiting, blocking absorption of the drug, and administering glucose injection may be necessary, and if symptoms of hypoglycemia are severe, immediate hospitalization is required. This medication has not established safety or efficacy in children, so it will not be used.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain of oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, and changes in urination.

Mild side effects

  • Headache
  • severe hunger
  • nausea
  • vomiting
  • fatigue
  • sleep disturbances
  • anxiety
  • aggression
  • decreased concentration
  • decreased agility or motivation
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  • depression
  • confusion
  • speech disorders
  • aphasia
  • visual disturbances
  • tremor
  • incomplete paralysis
  • sensory disturbances
  • dizziness
  • weakness
  • loss of self-control
  • transient mental confusion
  • drowsiness
  • shallow breathing
  • bradycardia
  • sweating
  • cold and clammy skin
  • tachycardia
  • hypertension
  • palpitations
  • angina pectoris
  • deep vein thrombosis
  • blurred vision
  • and abdominal fullness.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from exposure to air or moisture. Also, it is important to store it at a temperature between 1 and 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

Green rectangular tablet

Package unit

Bottle packaging: 30 tablets, 300 tablets

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.