Desmopressin Acetate 0.2 mg (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration.

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of treatment, following a treatment-free period of at least 1 week.

This medication may cause hyponatremia and water intoxication; therefore, especially elderly patients or certain patients should only drink enough water to relieve thirst. Patients with allergies to this medication or with specific conditions such as heart failure, kidney failure, and diabetes insipidus should not use it. Caution should be exercised when using this medication in patients with hypertension, chronic kidney disease, pregnant women or those who may become pregnant, children, and the elderly; related conditions should be treated first. During the use of this medication, serious symptoms of water intoxication such as coma, seizures, and weight gain may occur, so caution is necessary. Fluid intake should be restricted from one hour before administration to eight hours after administration of this medication; failure to do so may result in headaches, nausea, weight gain, and in severe cases, seizures. This medication may interact with other medications, so especially when taken with antidepressants, diuretics, steroids, and NSAIDs, consultation with a professional is necessary. Pregnant women should be careful while using this medication due to the risk of uterine contractions, and it is advisable to discontinue breastfeeding if nursing during treatment. In case of overdose, symptoms such as headache, nausea, seizures, and loss of consciousness may occur, so immediate consultation with healthcare professionals is required, and treatment such as fluid restriction and diuretic administration should be received if necessary.

• coma
• convulsions
• weight gain
• severe water intoxication
• hyponatremia
• allergic reactions
• emotional disturbances
• headache
• abdominal pain
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture, and the storage temperature should be maintained between 1 degree and 30 degrees Celsius. Storing it this way helps to maintain the effectiveness of the medication for a longer time.

Appearance

White or light yellow granules

Package unit

500mg/pack