Medication info

Danirinsereup 0.2 mg (Desmopressin Acetate)

Prescription medicationOralExpired
Ingredient · strength
Desmopressin Acetate›0.2mg / 1 packet
Manufacturer / importer
HanMi Pharmaceutical Co., Ltd.
Appearance
White or light yellow granular preparation
Packaging
1 packet (500 mg) x 30 packets/box
Approval status
Expired

MFDS item code 201403396 · Approved 2014.07.25

This product's status changed to Expired on 2024.07.25. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)
Who takes it
Adults · Children
Adult dose
Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration.
Child dose
Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of treatment, following a treatment-free period of at least 1 week.

Ingredients

Manufacturer
HanMi Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of primary nocturnal enuresis (age 5 years and older) and nocturia associated with nocturnal polyuria (adults)

  • Primary nocturnal enuresis
  • nocturia symptoms
View approved original text

Nocturnal enuresis primarily occurs in children over 5 years old and is characterized by frequent urination at night. In adults, it is used to treat nocturia related to nocturia symptoms. This medication is effective in improving enuresis symptoms and helping to achieve comfortable sleep. Therefore, it is used for treating primary nocturnal enuresis and nocturia in adults.

How to take

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) Administer 0.1mg of desmopressin acetate orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after dose titration.

Child dose

Primary nocturnal enuresis (age 5 years and older): Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after 3 months of treatment, following a treatment-free period of at least 1 week.

Precautions

This medication helps regulate the body's fluid balance, but caution is needed as hyponatremia and water intoxication can occur, especially in elderly patients or those with certain diseases. This medicine should not be used in patients who have had allergic reactions to its ingredients, those with severe heart failure or renal impairment, and patients with certain neurological disorders. Patients with hypertension or cardiovascular diseases, chronic kidney diseases, pregnant women or women who may become pregnant, and children and the elderly should use this medication with extra caution. Water intake should be limited while taking this medication, and it is especially important not to consume a lot of water for a certain period before and after administration. Side effects may include headaches, nausea, skin reactions, and hyponatremia; in severe cases, symptoms such as coma or seizures may occur, so if any unusual symptoms appear, consult a healthcare professional immediately. This medication may interact with other drugs, so if you are currently taking any medication, be sure to inform your doctor or pharmacist. Women who are pregnant or breastfeeding should make a careful decision considering the potential effects on the fetus or newborn, and it is recommended to discontinue breastfeeding while using this medication. In case of overdose, excessive fluid accumulation in the body can worsen hyponatremia, so if symptoms appear, visit a hospital immediately for appropriate treatment.

Side effects

  • coma
  • convulsion
  • weight gain
  • allergic reaction
  • hyponatremia
  • emotional disorder
  • headache
  • abdominal pain
  • nausea
  • allergic skin reaction
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  • dizziness
  • peripheral edema
  • frequent urination
  • thirst
  • vomiting
  • cold sensation
  • loss of consciousness

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine should be stored in a tightly sealed container to avoid exposure to air or moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the drug's efficacy and safety.

Appearance and packaging

Appearance

White or light yellow granular preparation

Package unit

1 packet (500 mg) x 30 packets/box

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.