Hapfen Soft Capsule (Naproxen)

Adult dose

For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Administer 250-500 mg of naproxen orally twice a day (every 12 hours). For acute gout: Administer 750 mg orally as the initial dose and then 250 mg orally every 8 hours until the attack resolves. For musculoskeletal disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendonitis, bursitis: Administer 500 mg orally as the initial dose and then 250 mg every 6-8 hours.

This medication should not be taken by individuals who regularly consume more than three drinks per day, as this increases the risk of gastrointestinal bleeding; consultation with a physician or pharmacist is essential. This drug can affect the cardiovascular system and may increase the risk of serious thrombotic reactions such as myocardial infarction and stroke, so caution is advised for those with cardiovascular disease or risk factors. This drug can cause severe adverse reactions such as gastrointestinal bleeding, ulcers, and perforations, especially among the elderly, so gastrointestinal symptoms should be monitored closely during treatment. Patients with a history of peptic ulcers, severe blood disorders, liver impairment, heart failure, kidney impairment, hypertension, drug hypersensitivity, or asthma should not take this medication. Patients with a history of peptic ulcers or blood disorders, bleeding tendencies, liver impairment, kidney impairment, heart failure, hypertension, hypersensitivity, asthma, autoimmune diseases, and the elderly should use this medication cautiously and follow their physician's instructions. During use, allergic reactions, gastrointestinal bleeding, blood disorders, liver dysfunction, kidney dysfunction, central nervous system disorders, skin rashes, and visual or auditory impairments may occur, so if any unusual symptoms arise, immediate consultation with a healthcare provider is necessary. This medication should be taken at the minimum dose for the shortest duration possible, and regular testing and monitoring are required during chronic disease treatment. Interactions may occur when used with other non-steroidal anti-inflammatory drugs (NSAIDs) or specific medications; therefore, inform your healthcare provider about any other medications you are taking. This medication should not be taken during pregnancy, especially in the late stages, as it may affect fetal kidney function after 20 weeks of gestation. Women who are breastfeeding should avoid this medication due to the potential transfer to breast milk and its effects on the neonate. It is recommended not to administer this drug to children, especially infants under 2 years of age, as safety has not been established. The elderly are at greater risk for side effects such as gastrointestinal bleeding; therefore, starting at a low dose and careful monitoring of adverse effects is advised. In case of overdose, symptoms such as drowsiness, indigestion, and vomiting may appear, and immediate help from a healthcare provider should be sought. This medication should be kept in a safe place out of the reach of children and should not be transferred to other containers to maintain its quality.

Serious side effects

• Rash, severe swelling (edema), cold sweat → severe allergic reaction
• Hematemesis, gastrointestinal bleeding, peptic ulcer, perforation → severe gastrointestinal adverse reaction
• Shortness of breath, wheezing, anaphylactic reaction → respiratory problems
• Yellowing of the skin (jaundice), hepatitis, jaundice → liver disorders (jaundice)
• Severe headache, aseptic meningitis, altered consciousness → severe neurological symptoms
• Sudden decrease in urine output, severe edema, increased blood pressure → severe edema or urination.

Mild side effects

• Nausea
• stomach pain
• abdominal pain
• vomiting
• loss of appetite
• indigestion
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs or naproxen derivatives. Phenytoin-based anticonvulsants, sulfonamides, sulfonylurea-based hypoglycemic agents, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin-based anticoagulants (such as warfarin), zidovudine, and fluoroquinolone antibiotics (such as enoxacin).

This medication should be stored in a sealed container to prevent exposure to air or moisture, and it is best stored at room temperature between 1 degree and 30 degrees.

Appearance

A greenish transparent oval soft capsule containing a colorless to pale green transparent content.

Package unit

10 capsules (10 capsules/PTP x 1)